A D Roses

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

Warren J. Strittmatter, Ann M. Saunders, D. E. Schmechel et al. · Proceedings of the National Academy of Sciences · 1993 · 4.3K citations · Full text

Life Sciences, Genetics, Neurology +17

Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease

Marcus E. Risner, Ann M. Saunders, Jill F.B. Altman et al. · The Pharmacogenomics Journal · 2006 · 681 citations

Medicine, Pharmacology, Pharmacotherapy +12

Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14

Peter St George‐Hyslop, Jonathan L. Haines, Marzia Mortilla et al. · Nature Genetics · 1992 · 463 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Apolipoprotein E Is Localized to the Cytoplasm of Human Cortical Neurons: A Light and Electron Microscopic Study

Seol‐Heui Han, Gillian Einstein, Karl H. Weisgraber et al. · Journal of Neuropathology & Experimental Neurology · 1994 · 195 citations

Medicine, Neurobiology, Neuroscience +11

Genome-wide approaches to identify pharmacogenetic contributions to adverse drug reactions

Matthew R. Nelson, Michael Mosteller, Ling-Ling Li et al. · The Pharmacogenomics Journal · 2008 · 107 citations

Medicine, Genetics, Pharmacology +16