David A. Patten

OPA1‐dependent cristae modulation is essential for cellular adaptation to metabolic demand

David A. Patten, Jacob Wong, Mireille Khacho et al. · The EMBO Journal · 2014 · 403 citations · Full text

Life Sciences, Biochemistry, Cell Biology +12

Translational up-regulation of the EGFR by tumor hypoxia provides a nonmutational explanation for its overexpression in human cancer

Aleksandra Franovic, Lakshman Gunaratnam, Karlene Smith et al. · Proceedings of the National Academy of Sciences · 2007 · 279 citations · Full text

Medicine, Molecular Biology, Oncology +16

Acidosis overrides oxygen deprivation to maintain mitochondrial function and cell survival

Mireille Khacho, Michelle Tarabay, David A. Patten et al. · Nature Communications · 2014 · 193 citations · Full text

Life Sciences, Biology, Cell Biology +17

Hypoxia-inducible Factor-1 Activation in Nonhypoxic Conditions: The Essential Role of Mitochondrial-derived Reactive Oxygen Species

David A. Patten, Véronique N. Lafleur, Geneviève Robitaille et al. · Molecular Biology of the Cell · 2010 · 174 citations · Full text

Life Sciences, Molecular Biology, Physiology +17

MCL-1Matrix maintains neuronal survival by enhancing mitochondrial integrity and bioenergetic capacity under stress conditions

Ujval Anilkumar, Mireille Khacho, Alexanne Cuillerier et al. · Cell Death and Disease · 2020 · 132 citations · Full text

Life Sciences, Cell Biology, Neuroscience +17