Dual-functional nanoparticles targeting amyloid plaques in the brains of Alzheimer's disease mice

Chi Zhang, Wan Xu, Xiaoyao Zheng, +4

Biomaterials

NanoparticlesNanomedicineAlzheimer's DiseaseEngineeringAmyloid Plaques +12

Intranasal nanoparticles of basic fibroblast growth factor for brain delivery to treat Alzheimer's disease

Chi Zhang, Jie Chen, Chengcheng Feng, +5

International Journal of Pharmaceutics

NanoparticlesNanomedicineAlzheimer's DiseaseEngineeringIntranasal Nanoparticles +8

Intranasal H102 Peptide-Loaded Liposomes for Brain Delivery to Treat Alzheimer’s Disease

Xiaoyao Zheng, Xiayan Shao, Chi Zhang, +6

Pharmaceutical Research

Lipid PreparationNanomedicineNeurodegenerative DiseasesAlzheimer's DiseaseEngineering +7

The potential use of H102 peptide-loaded dual-functional nanoparticles in the treatment of Alzheimer's disease

Chi Zhang, Xiaoyao Zheng, Wan Xu, +4

Journal of Controlled Release

NanoparticlesNanomedicineNeurodegenerative DiseasesAlzheimer's DiseaseEngineering +9

<i>Solanum tuberosum</i>lectin-conjugated PLGA nanoparticles for nose-to-brain delivery:<i>in vivo</i>and<i>in vitro</i>evaluations

Jie Chen, Chi Zhang, Qingfeng Liu, +5

Journal of drug targeting

PEGylated poly(2-(dimethylamino) ethyl methacrylate)/DNA polyplex micelles decorated with phage-displayed TGN peptide for brain-targeted gene delivery

Yong Qian, Yuan Zha, Bing Feng, +8

Biomaterials

/Dna Polyplex MicellesEngineeringPolymer-drug ConjugateBrain-targeted Gene DeliveryNano-drug Delivery +7

Dual-functional nanoparticles for precise drug delivery to Alzheimer’s disease lesions: Targeting mechanisms, pharmacodynamics and safety

Xiaoyao Zheng, Chi Zhang, Qian Guo, +4

International Journal of Pharmaceutics

NanoparticlesNanomedicineDrug TargetingAlzheimer's DiseaseDisease Lesions +9

Conjugating influenza a (H1N1) antigen to n‐trimethylaminoethylmethacrylate chitosan nanoparticles improves the immunogenicity of the antigen after nasal administration

Qingfeng Liu, Xiaoyao Zheng, Chi Zhang, +4

Journal of Medical Virology

NanoparticlesEngineeringNasal AdministrationImmunologyImmunotherapy +16

Enhancement of nose-to-brain delivery of basic fibroblast growth factor for improving rat memory impairments induced by co-injection of β-amyloid and ibotenic acid into the bilateral hippocampus

Chengcheng Feng, Chi Zhang, Xiayan Shao, +7

International Journal of Pharmaceutics

Neurodegenerative DiseasesMolecular NeuroscienceBrain DevelopmentBilateral HippocampusIbotenic Acid +10

In vivo toxicity and immunogenicity of wheat germ agglutinin conjugated poly(ethylene glycol)-poly(lactic acid) nanoparticles for intranasal delivery to the brain

Qingfeng Liu, Xiayan Shao, Jie Chen, +7

Toxicology and Applied Pharmacology

NanoparticlesNanomedicineEthylene GlycolWheat GermEngineering +6