Inhibitory effect of bombesin receptor antagonist RC-3095 on the growth of human pancreatic cancer cells in vivo and in vitro.

Yunfeng Qin, Tibor Ertl, Ren-Zhi Cai, +2

PubMed

Tumor Growth RateCancer BiologyTumor BiologyMolecular PharmacologyPancreatic Cancer +15

Design, synthesis, and <i>in vitro</i> evaluation of cytotoxic analogs of bombesin-like peptides containing doxorubicin or its intensely potent derivative, 2-pyrrolinodoxorubicin

Attila Nagy, Patricia Armatis, Ren-Zhi Cai, +3

Proceedings of the National Academy of Sciences

Biological effects and receptor binding affinities of new pseudononapeptide bombesin/GRP receptor antagonists with N‐terminal <scp>d</scp>‐Trp or <scp>d</scp>‐Tpi

Siniša Radulović, Ren-Zhi Cai, Péter Serfózó, +4

International journal of peptide & protein research

Luteinizing hormone-releasing hormone antagonist Cetrorelix (SB-75) and bombesin antagonist RC-3940-II inhibit the growth of androgen-independent PC-3 prostate cancer in nude mice

A. Jungwirth, Georg Galvan, Jacek Pinski, +5

The Prostate

Preclinical efficacy of growth hormone-releasing hormone antagonists for androgen-dependent and castration-resistant human prostate cancer

Cale D. Fahrenholtz, Ferenc G. Rick, María I. Rodríguez García, +5

Proceedings of the National Academy of Sciences

UrologyGrowth HormoneHuman GrowthMedicineHormonal Receptor +9

Antagonists of growth hormone releasing hormone (GHRH) and of bombesin/gastrin releasing peptide (BN/GRP) suppress the expression of VEGF, bFGF, and receptors of the EGF/HER family in PC-3 and DU-145 human androgen-independent prostate cancers

Anton Stangelberger, Andrew V. Schally, József L. Varga, +5

The Prostate

Beneficial effects of novel antagonists of GHRH in different models of Alzheimer's disease

Miklós Jászberényi, Ferenc G. Rick, Luca Szalontay, +4

Aging

Agonists of growth hormone-releasing hormone stimulate self-renewal of cardiac stem cells and promote their survival

Victoria Florea, Sonia S. Majid, Rosemeire M. Kanashiro‐Takeuchi, +5

Proceedings of the National Academy of Sciences

Inhibition of human androgen-independent PC-3 and DU-145 prostate cancers by antagonists of bombesin and growth hormone releasing hormone is linked to PKC, MAPK and c-jun intracellular signalling

Anton Stangelberger, Andrew V. Schally, József L. Varga, +6

European Journal of Cancer

UrologySignal TransductionGrowth HormoneSignaling PathwayReceptor Tyrosine Kinase +8

Novel GHRH antagonists suppress the growth of human malignant melanoma by restoring nuclear p27 function

Luca Szalontay, Andrew V. Schally, Petra Popovics, +7

Cell Cycle

Human GrowthNovel GhrhGrowth Hormone-releasing HormoneImmunotherapeuticsMalignant Melanoma +17