Weihua Wan

Anaplastic lymphoma kinase activity is essential for the proliferation and survival of anaplastic large-cell lymphoma cells

Weihua Wan, Mark S. Albom, Lihui Lü et al. · Blood · 2005 · 105 citations

Veterinary Medicine, Cell Biology, Oncology +11

Discovery of Clinical Candidate CEP-37440, a Selective Inhibitor of Focal Adhesion Kinase (FAK) and Anaplastic Lymphoma Kinase (ALK)

Gregory R. Ott, Mangeng Cheng, Keith S. Learn et al. · Journal of Medicinal Chemistry · 2016 · 90 citations · Full text

Medicine, Oncology, Pharmacology +17

CEP-28122, a Highly Potent and Selective Orally Active Inhibitor of Anaplastic Lymphoma Kinase with Antitumor Activity in Experimental Models of Human Cancers

Mangeng Cheng, Matthew R. Quail, Diane E. Gingrich et al. · Molecular Cancer Therapeutics · 2011 · 70 citations

Medicine, Oncology, Pharmacology +16

Discovery of a Potent Inhibitor of Anaplastic Lymphoma Kinase with in Vivo Antitumor Activity

Gregory R. Ott, Rabindranath Tripathy, Mangeng Cheng et al. · ACS Medicinal Chemistry Letters · 2010 · 49 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +15

2,7-Disubstituted-pyrrolo[2,1-<i>f</i>][1,2,4]triazines: New Variant of an Old Template and Application to the Discovery of Anaplastic Lymphoma Kinase (ALK) Inhibitors with in Vivo Antitumor Activity

Gregory R. Ott, Gregory J. Wells, Tho V. Thieu et al. · Journal of Medicinal Chemistry · 2011 · 42 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +15