PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor

Björn Hock, Beatrix Böhme, Thomas Karn, +7

Proceedings of the National Academy of Sciences

Ras-binding Protein Af6Signal Transduction PathwaysRegulate Signal TransductionSignaling PathwayPdz-domain-mediated Interaction +15

Generation and analysis of the improved human HAL9/10 antibody phage display libraries

Jonas Kügler, Sonja Wilke, Doris Meier, +9

BMC Biotechnology

A generic approach to engineer antibody pH-switches using combinatorial histidine scanning libraries and yeast display

Christian Schröter, Ralf Günther, Laura Rhiel, +9

mAbs

Biomolecular ToolMolecular BiologyGeneric ApproachAntibody Ph-switchesProtein Folding +18

Tyrosine-614, the major autophosphorylation site of the receptor tyrosine kinase HEK2, functions as multi-docking site for SH2-domain mediated interactions

Björn Hock, Beatrix Böhme, Thomas Karn, +3

Oncogene

Signal TransductionSignaling PathwayMolecular PathwayReceptor Tyrosine KinaseReceptor (Biochemistry) +7

Generation of human bispecific common light chain antibodies by combining animal immunization and yeast display

Simon Krah, Christian Schröter, Carla Eller, +9

Protein Engineering Design and Selection

Immunocytochemical TechniqueEngineeringImmunologyMolecular BiologyAnimal Immunization +19

Spontaneous Isopeptide Bond Formation as a Powerful Tool for Engineering Site-Specific Antibody-Drug Conjugates

Vanessa Siegmund, Birgit Piater, Bijan Zakeri, +8

Scientific Reports

Novel CH1:CL interfaces that enhance correct light chain pairing in heterodimeric bispecific antibodies

Maximilian Bönisch, Carolin Sellmann, Daniel Maresch, +5

Protein Engineering Design and Selection

EngineeringProtein AssemblyHeterodimeric Bispecific AntibodiesMolecular BiologyChemical Biology +16

REAL-Select: Full-Length Antibody Display and Library Screening by Surface Capture on Yeast Cells

Laura Rhiel, Simon Krah, Ralf Günther, +3

PLoS ONE

Immunocytochemical TechniqueEngineeringImmunologyMolecular BiologyImmunotherapy +17

Design of a Trispecific Checkpoint Inhibitor and Natural Killer Cell Engager Based on a 2 + 1 Common Light Chain Antibody Architecture

Jan P. Bogen, Stefania Carrara, David Fiebig, +3

Frontiers in Immunology

ImmunologyImmunoeditingImmunodominanceImmunotherapeuticsImmunotherapy +17

An online monitoring system based on a synthetic sigma32-dependent tandem promoter for visualization of insoluble proteins in the cytoplasm of Escherichia coli

Mario Kraft, Uwe Knüpfer, Rolf Wenderoth, +3

Applied Microbiology and Biotechnology

Functional GenomicsProtein ExpressionReporter Gene AssayNatural SciencesMedicine +11