Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl

Ellen Weisberg, Paul W. Manley, Werner Breitenstein, +18

Cancer Cell

Molecular PharmacologyMutant Bcr-ablMedicineSelective InhibitorMolecular Biology +3

Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritis

Karel Odink, Nico Cerletti, Josef Brüggen, +6

Nature

InflammationRheumatologyRheumatoid DisorderAutoimmune DiseaseImmunology +5

New Anilinophthalazines as Potent and Orally Well Absorbed Inhibitors of the VEGF Receptor Tyrosine Kinases Useful as Antagonists of Tumor-Driven Angiogenesis

Guido Bold, Karl‐Heinz Altmann, J Frei, +25

Journal of Medicinal Chemistry

Solid TumorPharmacotherapyTumor BiologyNew AnilinophthalazinesMedicinal Chemistry +18

Phenotypic dynamics of tumor progression in human malignant melanoma

Eva‐Bettina Bröcker, Ludwig Suter, Josef Brüggen, +3

International Journal of Cancer

Tumor ImmunologyCancer ImmunosurveillanceSkin CancerTumor HeterogeneityMelanoma +13

Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl

Ellen Weisberg, Paul W. Manley, Werner Breitenstein, +18

Cancer Cell

Molecular PharmacologyMutant Bcr-ablMedicineSelective InhibitorMolecular Biology +3

Anthranilic Acid Amides:  A Novel Class of Antiangiogenic VEGF Receptor Kinase Inhibitors

Paul W. Manley, Pascal Furet, Guido Bold, +13

Journal of Medicinal Chemistry

Angiogenesis InhibitorsPharmacotherapyTumor BiologyMedicinal ChemistryAngiogenesis +14

Use of an enzyme-linked immunosorbent assay (ELISA) for screening of hybridoma antibodies against cell surface antigens

Ludwig Suter, Josef Brüggen, Clemens Sorg

Journal of Immunological Methods

ImmunohematologyMolecular Diagnostic TechniquesAllergyBioanalysisImmunology +9

Urea derivatives of STI571 as inhibitors of Bcr-Abl and PDGFR kinases

Paul W. Manley, Werner Breitenstein, Josef Brüggen, +4

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryBiochemistryNatural SciencesMedicineUrea Derivatives +8

Modes of binding and internalization of monoclonal antibodies to human melanoma cell lines.

S. Matzku, Eva‐Bettina Bröcker, Josef Brüggen, +2

PubMed

Immunocytochemical TechniqueRadioactive MabMelanomaImmunologyMonoclonal Antibodies +9

Illuminating the Sites of Enterovirus Replication in Living Cells by Using a Split-GFP-Tagged Viral Protein

Hilde M. van der Schaar, Charlotte E. Melia, Josef Brüggen, +5

mSphere

Viral ReplicationMolecular VirologyElectron MicroscopyMedicinePathogenesis +12