Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats.

Jan Kajstura, Wei Cheng, Krzysztof Reiss, +6

PubMed

Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell.

Annarosa Leri, Pier Paolo Claudio, Q Li, +6

Journal of Clinical Investigation

ApoptosisImmunologyStretch-mediated ReleaseCell DeathCellular Physiology +16

Programmed Myocyte Cell Death Affects the Viable Myocardium after Infarction in Rats

Wei Cheng, Jan Kajstura, James A. Nitahara, +8

Experimental Cell Research

InflammationCardiac MuscleCardiomyopathyHeart FailureCardiovascular Disease +8

Overexpression of insulin-like growth factor-1 in the heart is coupled with myocyte proliferation in transgenic mice.

Krzysztof Reiss, Wei Cheng, Andres Ferbér, +7

Proceedings of the National Academy of Sciences

Cardiac MuscleTransgenic Mouse ModelsCardiac Progenitor CellsTransgenic MiceInsulin Signaling +17

Subpopulations of myeloid‐derived suppressor cells impair T cell responses through independent nitric oxide‐related pathways

Patrick Raber, Paul Thevenot, Rosa A. Sierra, +9

International Journal of Cancer

Nitric OxideT-regulatory CellImmune RegulationImmunologyImmunotherapy +14

A dominant negative mutant of the insulin-like growth factor-I receptor inhibits the adhesion, invasion, and metastasis of breast cancer.

Sandra E. Dunn, Melanie Ehrlich, N J Sharp, +5

PubMed

Tumor BiologyBreast OncologyMedicineImmunologyCancer Growth +13

Necrotic and apoptotic myocyte cell death in the aging heart of Fischer 344 rats

Jan Kajstura, Wei Cheng, P. Li, +6

American Journal of Physiology-Heart and Circulatory Physiology

InflammationLifespan ExtensionCardiac MuscleAgingLongevity +13

Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice

Carolyn A. Pedone, Luis Del Valle, Krzysztof Reiss, +2

Oncogene

Developmental BiologyEpendymaInsulin-like Growth FactorMedicineCell Interaction +7

Beta-amyloid deposition and Alzheimer's type changes induced by Borrelia spirochetes

Judith Miklossy, András Kis, Lisa M. Miller, +6

Neurobiology of Aging

Beta-amyloid DepositionAlzheimer's DiseaseMedicineDementiaDegenerative Pathology +6

Programmed Cell Death and Expression of the Protooncogene bcl-2 in Myocytes during Postnatal Maturation of the Heart

Jan Kajstura, Mahesh Mansukhani, Wei Cheng, +6

Experimental Cell Research

Cardiac MuscleCardiomyopathyDevelopmental BiologyCell DivisionMedicine +11