Ryozo Hayashi

Optical inversion of (2R)- to (2S)-isomers of 2-(4-(2-oxocyclopentylmethyl)-phenyl)propionic acid (loxoprofen), a new anti-inflammatory agent, and its monohydroxy metabolites in the rat.

Hisomu NAGASHIMA, Yorihisa Tanaka, Hidetoshi Watanabe et al. · Chemical and Pharmaceutical Bulletin · 1984 · 35 citations · Full text

Pharmaceutical Science, Pharmacotherapy, Pharmaceutical Chemistry +18

Species differences in metabolism of sodium 2-(4-(2-oxocyclopentylmethyl)phenyl)propionate dihydrate (loxoprofen sodium), a new anti-inflammatory agent.

Yorihisa Tanaka, Yuko Nishikawa, Ryozo Hayashi · Chemical and Pharmaceutical Bulletin · 1983 · 31 citations · Full text

Pharmacotherapy, Species Differences, Inflammation +18

Column liquid chromatography for the simultaneous determination of the enantiomers of loxoprofen sodium and its metabolites in human urine

Hisomu NAGASHIMA, Yorihisa Tanaka, Ryozo Hayashi · Journal of Chromatography B Biomedical Sciences and Applications · 1985 · 31 citations

Human Urine, Loxoprofen Sodium, Medicine +11

Purification and some properties of ketone reductase forming an active metabolite of sodium 2-(4-(2-oxocyclopentylmethyl)phenyl)propionate dihydrate(loxoprofen sodium), a new anti-inflammatory agent, in rabbit liver cytosol.

Yorihisa Tanaka, Yuko Nishikawa, Keiichi Matsuda et al. · Chemical and Pharmaceutical Bulletin · 1984 · 25 citations

Molecular Pharmacology, Ketone Reductase, Anti-inflammatory +14

Studies on the Total Synthesis of dl-Colchiceine. I. Synthesis of 3-Hydroxy-9, 10, 11-trimethoxy-1, 2, 3, 4, 6, 7-hexahydro-5H-dibenzo [a, c] cycloheptatrien-5-one.

Takahiro Nakamura, Yasuhiro Murase, Ryozo Hayashi et al. · Chemical and Pharmaceutical Bulletin · 1962 · 19 citations · Full text

Bioorganic Chemistry, Heterocyclic, Seven-membered Ring +11