Activation of Retinoic Acid Receptor-dependent Transcription by All-trans-retinoic Acid Metabolites and Isomers

Nadia Idres, Julie Marill, Maria Flexor, +1

Journal of Biological Chemistry

Atra MetabolitesOxidative StressTranscriptional RegulationAll-trans-retinoic AcidCell Regulation +14

Retinoids down-regulate telomerase and telomere length in a pathway distinct from leukemia cell differentiation

Frédéric Pendino, Maria Flexor, François Delhommeau, +3

Proceedings of the National Academy of Sciences

Synergic effects of arsenic trioxide and cAMP during acute promyelocytic leukemia cell maturation subtends a novel signaling cross-talk

Qi Zhu, Jiwang Zhang, Haiqing Zhu, +10

Blood

A mutated PML/RARA found in the retinoid maturation resistant NB4 subclone, NB4-R2, blocks RARA and wild-type PML/RARA transcriptional activities

Estelle Duprez, G Benoît, Maria Flexor, +2

Leukemia

ChromatinGeneticsMutated Pml/raraGene RegulationMolecular Genetics +4

Granulocytic differentiation of human NB4 promyelocytic leukemia cells induced by all-trans retinoic acid metabolites.

Nadia Idres, G Benoît, Maria Flexor, +2

PubMed

Atra MetabolismMixed-phenotype Acute LeukemiaGranulocytic DifferentiationCell ProliferationAll-trans Retinoic Acid +14

Autonomous Rexinoid Death Signaling Is Suppressed by Converging Signaling Pathways in Immature Leukemia Cells

G Benoît, Maria Flexor, Françoise Besançon, +8

Molecular Endocrinology

Postmaturation ApoptosisRetinoic Acid ReceptorApoptosisCell DeathTumor Biology +16

Retinoic acid receptor α and retinoid-X receptor-specific agonists synergistically target telomerase expression and induce tumor cell death

Frédéric Pendino, Charles Dudognon, François Delhommeau, +5

Oncogene

Telomerase ExpressionCancer ResearchCell RegulationMedicineApoptosis +8

Alteration of 5′‐Nucleotidase and Na⁺, K⁺‐ATPase in Central and Peripheral Nervous Tissue from Dysmyelinating Mutants (jimpy, quaking, Trembler, shiverer, and mld). Comparison with CNPase in the Developing Sciatic Nerve from Trembler

J.M. Bourre, C. Chanez, Odile Dumont, +1

Journal of Neurochemistry

Developing Sciatic NerveNeurological DisorderSynaptic TransmissionPeripheral NervePeripheral Nerves +26

Apoptosome-independent Pathway for Apoptosis

Chafké Ahmed Belmokhtar, Josette Hillion, Charles Dudognon, +4

Journal of Biological Chemistry

Influence of Intrauterine Malnutrition on Brain Development: Alteration of Myelination

J.M. Bourre, O. Morand, C. Chanez, +2

Neonatology

NutritionBrain DevelopmentFetal MedicineBrain NutritionEmbryology +17