Nicole R. Higdon

A Novel Positive Allosteric Modulator of the α7 Neuronal Nicotinic Acetylcholine Receptor:<i>In Vitro</i>and<i>In Vivo</i>Characterization

Raymond S Hurst, Mihály Hajós, M. Raggenbass et al. · Journal of Neuroscience · 2005 · 441 citations · Full text

Traumatic Brain Injury, Synaptic Transmission, Neurotransmitter +18

The Selective α7 Nicotinic Acetylcholine Receptor Agonist PNU-282987 [N-[(3 R)-1-Azabicyclo[2.2.2]oct-3-yl]-4-chlorobenzamide Hydrochloride] Enhances GABAergic Synaptic Activity in Brain Slices and Restores Auditory Gating Deficits in Anesthetized Rats

Mihály Hajós, Raymond S Hurst, William E. Hoffmann et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 223 citations

Discovery and Structure−Activity Relationship of Quinuclidine Benzamides as Agonists of α7 Nicotinic Acetylcholine Receptors

Alice L. Bodnar, Luz Cortes-Burgos, Karen K. Cook et al. · Journal of Medicinal Chemistry · 2005 · 214 citations · Full text

Pharmacotherapy, Chemical Biology, Molecular Pharmacology +19

Discovery of<i>N</i>-[(3<i>R</i>)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-<i>c</i>]pyridine-5-carboxamide, an Agonist of the α7 Nicotinic Acetylcholine Receptor, for the Potential Treatment of Cognitive Deficits in Schizophrenia:  Synthesis and Structure−Activity Relationship

Donn G. Wishka, Daniel P. Walker, Karen M. Yates et al. · Journal of Medicinal Chemistry · 2006 · 188 citations · Full text

Neuropsychology, Compound 14, Psychopharmacology +23

Design, synthesis, structure–activity relationship, and in vivo activity of azabicyclic aryl amides as α7 nicotinic acetylcholine receptor agonists

Daniel P. Walker, Donn G. Wishka, David W. Piotrowski et al. · Bioorganic & Medicinal Chemistry · 2006 · 94 citations

Structure–activity Relationship, Vivo Activity, Biochemistry +8