Human pancreatic islet beta-cell destruction by cytokines involves oxygen free radicals and aldehyde production.

Alexander Rabinovitch, Wilma L. Suarez‐Pinzon, K Strynadka, +2

The Journal of Clinical Endocrinology & Metabolism

Nitric OxideLipid PeroxidationAldehyde ProductionImmunologyCell Death +20

Islet Xenotransplantation Using Gal-Deficient Neonatal Donors Improves Engraftment and Function

P. W. Thompson, I.R. Badell, Michael Lowe, +12

American Journal of Transplantation

Regenerative MedicineIslet TransplantationTransplantationXenotransplantationDevelopmental Biology +6

Testicular sertoli cells protect islet beta-cells from autoimmune destruction in NOD mice by a transforming growth factor-beta1-dependent mechanism.

Wilma L. Suarez‐Pinzon, G S Korbutt, R. Power, +3

Diabetes

Lymphocyte DevelopmentImmune RegulationImmunologyImmunologic MechanismTesticular Sertoli Cells +18

In vitro and in vivo expression of Galalpha-(1,3)Gal on porcine islet cells is age dependent

GR Rayat, R V Rajotte, Hering Bj, +2

Journal of Endocrinology

ImmunologyImmune RegulationPancreas TransplantationCellular PhysiologyInsulin Signaling +17

Beta-cell destruction in NOD mice correlates with Fas (CD95) expression on beta-cells and proinflammatory cytokine expression in islets.

Wilma L. Suarez‐Pinzon, R. Chris Bleackley, John F. Elliott, +2

Diabetes

ImmunologyCell DeathImmunologic MechanismNod Mice CorrelatesPancreas Transplantation +22

Expression of Gal alpha(1,3)gal on neonatal porcine islet beta-cells and susceptibility to human antibody/complement lysis.

Gina R. Rayat, R V Rajotte, John F. Elliott, +1

Diabetes

T cell activation and anergy to islet cell antigen in type I diabetes.

Isao Miyazaki, Roy K. Cheung, Roger Gaedigk, +4

The Journal of Immunology

T-regulatory CellImmunologyImmune RegulationT CellsImmunotherapy +16

TNF-alpha down-regulates type 1 cytokines and prolongs survival of syngeneic islet grafts in nonobese diabetic mice

Alexander Rabinovitch, Wilma L. Suarez‐Pinzon, R V Rajotte, +1

The Journal of Immunology

Natural human antibody‐mediated destruction of porcine neonatal islet cell grafts

G Korbutt, Launa J. Aspeslet, R V Rajotte, +6

Xenotransplantation

ImmunologyImmune RegulationImmunodominanceAntigen ProcessingPancreas Transplantation +22

Microencapsulated dog and rat islet xenografts into streptozotocin-diabetic and NOD mice.

Weber Cj, S Zabinsi, T Koschitzky, +5

PubMed

Tissue EngineeringViable IsletsEngineeringImmunologyBiomedical Engineering +15