J P Jaffrézou

Daunorubicin-induced apoptosis: triggering of ceramide generation through sphingomyelin hydrolysis.

J P Jaffrézou, Thierry Levade, Christine Bezombes et al. · The EMBO Journal · 1996 · 372 citations · Full text

Daunorubicin-induced Apoptosis, Biochemistry, Medicine +5

p38 MAPK mediates the regulation of α1(I) procollagen mRNA levels by TNF‐α and TGF‐β in a cell line of rat hepatic stellate cells¹

Marta Varela‐Rey, Cristina Montiel‐Duarte, Juan A. Osés-Prieto et al. · FEBS Letters · 2002 · 93 citations · Full text

Prevalence of multidrug resistance related to activation of the mdr1 gene in human sarcoma mutants derived by single-step doxorubicin selection.

Kevin G. Chen, J P Jaffrézou, William H. Fleming et al. · PubMed · 1994 · 85 citations

Immunology, Pathology, Multidrug Resistance +18

The protein kinase C activators phorbol esters and phosphatidylserine inhibit neutral sphingomyelinase activation, ceramide generation, and apoptosis triggered by daunorubicin.

V Mansat, G. Laurent, Thierry Levade et al. · PubMed · 1997 · 80 citations

Apoptosis, Cell Death, Ceramide Generation +16

Acidic sphingomyelinase-generated ceramide is needed but not sufficient for TNF-induced apoptosis and nuclear factor-kappa B activation

Masahiro Higuchi, Sujay Singh, J P Jaffrézou et al. · The Journal of Immunology · 1996 · 80 citations