Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis

Andreas M. Kaiser, Ashok K. Saluja, A. Sengupta, +2

American Journal of Physiology-Cell Physiology

Mild PancreatitisApoptosisImmunologyGastroenterologyCell Death +14

Subcellular redistribution of lysosomal enzymes during caerulein-induced pancreatitis

A. Saluja, S. Hashimoto, M. Saluja, +3

American Journal of Physiology-Gastrointestinal and Liver Physiology

GastroenterologyCytoskeletonSubcellular RedistributionDigestive TractCellular Physiology +20

Acute necrotizing pancreatitis in the opossum: Earliest morphological changes involve acinar cells

Markus M. Lerch, Ashok K. Saluja, Rajinder Dawra, +3

Gastroenterology

PathologyEarliest Morphological ChangesAnatomyMedicineAcinar Cells

Pancreatic duct obstruction in rabbits causes digestive zymogen and lysosomal enzyme colocalization.

Ashok K. Saluja, M. Saluja, Alessandro Villa, +4

Journal of Clinical Investigation

Animal PhysiologyBiochemistryPancreatic Duct ObstructionFood DigestionPhysiology +13

In vivo rat pancreatic acinar cell function during supramaximal stimulation with caerulein

A. Saluja, I. Saito, M. Saluja, +4

American Journal of Physiology-Gastrointestinal and Liver Physiology

Supramaximal StimulationProtein SecretionPancreas TransplantationCellular PhysiologySupramaximal Dose +15

Experimental pancreatitis is mediated by low-affinity cholecystokinin receptors that inhibit digestive enzyme secretion.

Ashok K. Saluja, M. Saluja, H. Printz, +3

Proceedings of the National Academy of Sciences

InflammationSignal TransductionAcute Edematous PancreatitisExperimental PancreatitisLow-affinity Cck Receptors +11

Apical secretion of lysosomal enzymes in rabbit pancreas occurs via a secretagogue regulated pathway and is increased after pancreatic duct obstruction.

Tatsuya Hirano, Ashok K. Saluja, Poduri Ramarao, +3

Journal of Clinical Investigation

Protein SecretionApical SecretionGastroenterologyPathologyCorrelated Apical Secretion +16

The role of oxygen-derived free radicals in two models of experimental acute pancreatitis: Effects of catalase, superoxide dismutase, dimethylsulfoxide, and allopurinol

Michael L. Steer, P Rutledge, Robert E. Powers, +2

Journal of Molecular Medicine

InflammationOxygen-derived Free RadicalsOxysterolBiochemistryMedicine +10

Stimulation of Pancreatic Growth by Cholecystokinin Is Mediated by High-Affinity Receptors on Rat Pancreatic Acinar Cells

Rajinder Dawra, Ashok K. Saluja, Markus M. Lerch, +3

Biochemical and Biophysical Research Communications

Molecular PhysiologySignal TransductionCholecystokinin IsPhysiologyHigh-affinity Receptors +8

A plasma protease which is expressed during supramaximal stimulation causes in vitro subcellular redistribution of lysosomal enzymes in rat exocrine pancreas.

M. Saluja, Ashok K. Saluja, Markus M. Lerch, +1

Journal of Clinical Investigation

Protein SecretionProteasomeCytoskeletonCathepsin B RedistributionDigestive Tract +19