J A Sharpe - Concepedia

Concepedia

Author

J A Sharpe

John Radcliffe Hospital

Also Known As

J A Sharpe, J Sharpe, J. A. Sharpe, J. Sharpe, J.A. Sharpe, Jackie A Sharpe, Jackie A. Sharpe, Jackie Sharpe, Julianne Sharpe, Sharpe, J.

34

Publications

1.8K

Citations

14

H-Index

43

Concepts

All Affiliations

John Radcliffe Hospital University of Oxford University of Edinburgh MRC Weatherall Institute of Molecular Medicine

JA

About

J A Sharpe is an author at John Radcliffe Hospital specializing in genetics, medicine, and gene expression.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	10	10	1.6K
2	Cell Biology	7	7	828
3	Natural Sciences	4	4	524
4	Cellular Physiology	1	1	159
5	Immunology	1	1	541

J A Sharpe

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14

Publications

1.8K

Citations

14

H-Index

	Year	Citations
Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease Cristina Tufarelli, Jackie A Sloane Stanley, David Garrick, Nature Genetics Genetic DiseasesAntisense RnaNovel CauseGeneticsDna Methylation	2003	541
A major positive regulatory region located far upstream of the human alpha-globin gene locus. Douglas R. Higgs, W. G. Wood, Andrew P. Jarman, Genes & Development Knockout MouseTranscriptional RegulationImmunogeneticsHuman Alpha MrnaGenetic Disorder	1990	347
Manipulating the Mouse Genome to Engineer Precise Functional Syntenic Replacements with Human Sequence Helen A. C. Wallace, Fatima Marques-Kranc, Melville Richardson, Cell BioinformaticsKnockout MouseTransgenic Mouse ModelsNatural SciencesGenetics	2007	164
Loss of Atrx Affects Trophoblast Development and the Pattern of X-Inactivation in Extraembryonic Tissues David Garrick, J A Sharpe, Ruth M. Arkell, PLoS Genetics GeneticsMolecular GeneticsReproductive BiologyCell SpecializationEpigenetics	2006	159
Alpha-thalassemia caused by a large (62 kb) deletion upstream of the human alpha globin gene cluster CS Hatton, H.C. Drysdale, WG Wood, Blood	1990	109
Characterization of the major regulatory element upstream of the human alpha-globin gene cluster. Andrew P. Jarman, W. G. Wood, J A Sharpe, Molecular and Cellular Biology GeneticsMolecular BiologyGene CharacterizationMolecular GeneticsGene Regulatory Network	1991	108
Contrasting effects of alpha and beta globin regulatory elements on chromatin structure may be related to their different chromosomal environments. Charles Craddock, Paresh Vyas, J A Sharpe, The EMBO Journal ChromatinSystems BiologyChromatin StructureChromatin RemodelingNatural Sciences	1995	93
Analysis of the human alpha globin upstream regulatory element (HS-40) in transgenic mice. J A Sharpe, Penny S. Chan‐Thomas, J. Lida, The EMBO Journal Transcriptional RegulationSignal TransductionProtein ExpressionHeme HomeostasisGenetics	1992	72
Analysis of the human alpha-globin gene cluster in transgenic mice. J A Sharpe, Dominic J. Wells, Emma Whitelaw, Proceedings of the National Academy of Sciences GeneticsGenomic MechanismGene CharacterizationMolecular GeneticsDisease Gene Identification	1993	65
A single beta-globin locus control region element (5' hypersensitive site 2) is sufficient for developmental regulation of human globin genes in transgenic mice. Bernard J. Morley, Caroline A. Abbott, J A Sharpe, Molecular and Cellular Biology Knockout MouseSingle Lcr ElementHuman Globin GenesBeta-globin Gene ComplexDevelopmental Biology	1992	56

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