J A Sharpe

Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease

Cristina Tufarelli, Jackie A Sloane Stanley, David Garrick et al. · Nature Genetics · 2003 · 548 citations

Life Sciences, Genetics, Molecular Genetics +16

A major positive regulatory region located far upstream of the human alpha-globin gene locus.

Douglas R. Higgs, W. G. Wood, Andrew P. Jarman et al. · Genes & Development · 1990 · 348 citations · Full text

Life Sciences, Genetics, Molecular Genetics +7

Manipulating the Mouse Genome to Engineer Precise Functional Syntenic Replacements with Human Sequence

Helen A. C. Wallace, Fatima Marques-Kranc, Melville Richardson et al. · Cell · 2007 · 165 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Loss of Atrx Affects Trophoblast Development and the Pattern of X-Inactivation in Extraembryonic Tissues

David Garrick, J A Sharpe, Ruth M. Arkell et al. · PLoS Genetics · 2006 · 160 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Alpha-thalassemia caused by a large (62 kb) deletion upstream of the human alpha globin gene cluster

CS Hatton, H.C. Drysdale, WG Wood et al. · Blood · 1990 · 109 citations

Life Sciences, Genetics, Molecular Genetics +9