Bryan G. Johnson

Discovery of a Potent, Peripherally Selective trans-3,4-Dimethyl-4-(3-hydroxyphenyl)piperidine Opioid Antagonist for the Treatment of Gastrointestinal Motility Disorders

Dennis M. Zimmerman, J. S. Gidda, Buddy E. Cantrell et al. · Journal of Medicinal Chemistry · 1994 · 118 citations · Full text

Gastrointestinal Motility Disorders, Gastroenterology, Pharmacotherapy +18

Inhibition of Excitatory Amino Acid‐Stimulated Phosphoinositide Hydrolysis in the Neonatal Rat Hippocampus by 2‐Amino‐3‐Phosphonopropionate

Darryle D. Schoepp, Bryan G. Johnson · Journal of Neurochemistry · 1989 · 114 citations

[3H]-LY341495 as a novel antagonist radioligand for group II metabotropic glutamate (mGlu) receptors: characterization of binding to membranes of mGlu receptor subtype expressing cells

Bryan G. Johnson, Rebecca A. Wright, M. Brian Arnold et al. · Neuropharmacology · 1999 · 100 citations

Mglu Receptor Subtype, Molecular Physiology, Signal Transduction +10

Selective inhibition of excitatory amino acid-stimulated phosphoinositide hydrolysis in the rat hippocampus by activation of protein kinase C

Darryle D. Schoepp, Bryan G. Johnson · Biochemical Pharmacology · 1988 · 78 citations

Rat Hippocampus, Selective Inhibition, Synaptic Plasticity +14

(1<i>S</i>,3<i>R</i>)‐1‐Aminocyclopentane‐1,3‐Dicarboxylic Acid‐Induced Increases in Cyclic AMP Formation in the Neonatal Rat Hippocampus Are Mediated by a Synergistic Interaction Between Phosphoinositide‐ and Inhibitory Cyclic AMP‐Coupled mGluRs

Darryle D. Schoepp, Bryan G. Johnson, James A. Monn · Journal of Neurochemistry · 1996 · 47 citations

Cyclic Amp Formation, Synaptic Transmission, Neurotransmitter +22