Thomas I.F.H. Cremers

(–)-(1 R,2 R)-3-(3-Dimethylamino-1-ethyl-2-methyl-propyl)-phenol Hydrochloride (Tapentadol HCl): a Novel μ-Opioid Receptor Agonist/Norepinephrine Reuptake Inhibitor with Broad-Spectrum Analgesic Properties

Thomas Tzschentke, Thomas Christoph, Babette Kögel et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 389 citations

Pre‐clinical properties of the α4β2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence

Hans Rollema, Alka Shrikhande, KM Ward et al. · British Journal of Pharmacology · 2010 · 162 citations · Full text

Inactivation of 5-HT2C Receptors Potentiates Consequences of Serotonin Reuptake Blockade

Thomas I.F.H. Cremers, Marco Giorgetti, Fokko J. Bosker et al. · Neuropsychopharmacology · 2004 · 157 citations · Full text

Molecular Pharmacology, Functional Selectivity, Medicine +7

Lu AA21004, a novel multimodal antidepressant, produces regionally selective increases of multiple neurotransmitters—A rat microdialysis and electrophysiology study

Alan L. Pehrson, Thomas I.F.H. Cremers, Cécile Betry et al. · European Neuropsychopharmacology · 2012 · 155 citations

Lu Aa21004, Psychiatry, Medicine +11

S32006, a novel 5-HT2C receptor antagonist displaying broad-based antidepressant and anxiolytic properties in rodent models

Anne Dekeyne, Clotilde Mannoury la Cour, Alain P. Gobert et al. · Psychopharmacology · 2008 · 124 citations

Psychiatry, Functional Selectivity, Medicine +12