Thomas I.F.H. Cremers

(–)-(1 R,2 R)-3-(3-Dimethylamino-1-ethyl-2-methyl-propyl)-phenol Hydrochloride (Tapentadol HCl): a Novel μ-Opioid Receptor Agonist/Norepinephrine Reuptake Inhibitor with Broad-Spectrum Analgesic Properties

Thomas Tzschentke, Thomas Christoph, Babette Kögel et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 394 citations

Medicine, Pharmacology, Pharmacotherapy +16

Pre‐clinical properties of the α4β2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence

Hans Rollema, Alka Shrikhande, KM Ward et al. · British Journal of Pharmacology · 2010 · 166 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Inactivation of 5-HT2C Receptors Potentiates Consequences of Serotonin Reuptake Blockade

Thomas I.F.H. Cremers, Marco Giorgetti, Fokko J. Bosker et al. · Neuropsychopharmacology · 2004 · 157 citations

Medicine, Neuroscience, Pharmacology +14

Lu AA21004, a novel multimodal antidepressant, produces regionally selective increases of multiple neurotransmitters—A rat microdialysis and electrophysiology study

Alan L. Pehrson, Thomas I.F.H. Cremers, Cécile Betry et al. · European Neuropsychopharmacology · 2012 · 156 citations

Medicine, Neuroscience, Pharmacology +15

S32006, a novel 5-HT2C receptor antagonist displaying broad-based antidepressant and anxiolytic properties in rodent models

Anne Dekeyne, Clotilde Mannoury la Cour, Alain P. Gobert et al. · Psychopharmacology · 2008 · 125 citations

Medicine, Medicinal Chemistry, Pharmacology +17