Pieter A. M. van der Klein

Allosteric Modulation of the Adenosine A₁ Receptor. Synthesis and Biological Evaluation of Novel 2-Amino-3-benzoylthiophenes as Allosteric Enhancers of Agonist Binding

Pieter A. M. van der Klein, Angeliki P. Kourounakis, Adriaan P. IJzerman · Journal of Medicinal Chemistry · 1999 · 92 citations · Full text

5‘-<i>O</i>-Alkyl Ethers of<i> N</i>,2-Substituted Adenosine Derivatives:  Partial Agonists for the Adenosine A₁ and A₃ Receptors

Erica W. van Tilburg, Pieter A. M. van der Klein, Jacobien von Frijtag Drabbe Künzel et al. · Journal of Medicinal Chemistry · 2001 · 41 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Adenosine A1 +15

Elucidation of structure-activity relationships of 2-amino-3-benzoylthiophenes: Study of their allosteric enhancing vs. antagonistic activity on adenosine A1 receptors

Angeliki P. Kourounakis, Pieter A. M. van der Klein, Adriaan P. IJzerman · Drug Development Research · 2000 · 34 citations · Full text

Organic Chemistry, Peptide Science, Heterocycle Chemistry +22

Iodonium Ion Promoted Cyclization: A Convenient Approach to Glycosyl Donors of 3-Deoxy-D-<i>manno</i>-2-octulosonic Acid (KDO)

Pieter A. M. van der Klein, Geert‐Jan Boons, G.H. Veeneman et al. · Synlett · 1990 · 26 citations

Glycosyl Donors, Novel Organocatalysts, Bioorganic Chemistry +15

Synthesis and biological evaluation of disubstituted N6-cyclopentyladenine analogues

Rianne A.F. de Ligt, Pieter A. M. van der Klein, Jacobien K. von Frijtag Drabbe Künzel et al. · Bioorganic & Medicinal Chemistry · 2003 · 24 citations

Organic Chemistry, Pharmacology, Heterocyclic +1