Structural characterization of the complete human perlecan gene and its promoter.

I. Cohen, S. Grässel, Alan D. Murdoch, +1

Proceedings of the National Academy of Sciences

Differential transcriptome analysis of intraarticular lesional vs intact cartilage reveals new candidate genes in osteoarthritis pathophysiology

Matthias Geyer, S. Grässel, Rainer H. Straub, +6

Osteoarthritis and Cartilage

Musculoskeletal ResearchBone Morphogenic ProteinGeneticsGene ExpressionCartilage Degeneration +8

Norepinephrine modulates osteoarthritic chondrocyte metabolism and inflammatory responses

Julia Lorenz, Nicole Schäfer, Robert Bauer, +3

Osteoarthritis and Cartilage

InflammationInflammatory ResponsesAnti-inflammatoryMusculoskeletal ResearchPhysiology +5

Alteration of fracture stability influences chondrogenesis, osteogenesis and immigration of macrophages

Stefan Hankemeier, S. Grässel, G. Plenz, +3

Journal of Orthopaedic Research®

Effect of hypoxia and reoxygenation on gene expression and response to interleukin‐1 in cultured articular chondrocytes

Grégoire Martin, Rina Andriamanalijaona, S. Grässel, +7

Arthritis & Rheumatism

Biomechanical forces exert anabolic effects on osteoblasts by activation of SMAD 1/5/8 through type 1 BMP receptor

Björn Rath, Jin Nam, James Deschner, +5

Biorheology

Tissue EngineeringSclerostinEngineeringBiomechanical ForcesOsteogenesis +22

Sympathectomy aggravates subchondral bone changes during osteoarthritis progression in mice without affecting cartilage degeneration or synovial inflammation

Gundula Rösch, Karima El Bagdadi, Dominique Muschter, +8

Osteoarthritis and Cartilage

RheumatologySubchondral Bone ChangesBone Morphogenic ProteinImmunologyCartilage Degeneration +9

Enhanced cartilage regeneration in MIA/CD-RAP deficient mice

R. Schmid, Susanne Schiffner, Alfred Opolka, +4

Cell Death and Disease

ImmunologyBone RepairMusculoskeletal ResearchRegenerative MedicineBone Morphogenic Protein +14

Synergistic effects of growth and differentiation factor-5 (GDF-5) and insulin on expanded chondrocytes in a 3-D environment

Bernhard Appel, Daniela Eyrich, Hatem A. Sarhan, +7

Osteoarthritis and Cartilage

Regenerative MedicineMechanobiologyTissue EngineeringExpanded ChondrocytesEngineering +12

Distinctive inhibition of the lysosomal targeting of lysozyme and cathepsin D by drugs affecting pH gradients and protein kinase C

J Radons, U Biewusch, S. Grässel, +2

Biochemical Journal