Nonsteroidal Anti-Inflammatory Drugs Can Lower Amyloidogenic Aß ₄₂ by Inhibiting Rho

Yan Zhou, Su Yuan, Baolin Li, +9

Science

Neurochemical BiomarkersOxidative StressInflammationAlzheimer's DiseaseDegenerative Pathology +14

Lithium, a Common Drug for Bipolar Disorder Treatment, Regulates Amyloid-β Precursor Protein Processing

Su Yuan, John Ryder, Baolin Li, +8

Biochemistry

Social SciencesMolecular PharmacologyAlzheimer's DiseaseDegenerative PathologyProtein Misfolding +17

Activation of a caspase 3-related cysteine protease is required for glutamate-mediated apoptosis of cultured cerebellar granule neurons

Yansheng Du, Kelly R. Bales, Richard C. Dodel, +6

Proceedings of the National Academy of Sciences

Function of the SIRT1 protein deacetylase in cancer

Walter Stünkel, Bee Keow Peh, Yong Tan, +6

Biotechnology Journal

Depolarization or glutamate receptor activation blocks apoptotic cell death of cultured cerebellar granule neurons

Yan Guang-mei, Binhui Ni, Michael Weller, +2

Brain Research

NeurophysiologyCell DeathNeuropharmacologyNeuroprotectionNeuroscience +8

Transient Global Forebrain Ischemia Induces a Prolonged Expression of the Caspase-3 mRNA in Rat Hippocampal CA1 Pyramidal Neurons

Binhui Ni, Xin Wu, Su Yuan, +4

Journal of Cerebral Blood Flow & Metabolism

Cell DeathProlonged ExpressionNeurotransmissionCellular PhysiologyTransient Forebrain Ischemia +18

SIRT1 Modulating Compounds from High-Throughput Screening as Anti-Inflammatory and Insulin-Sensitizing Agents

Vasantha M. Nayagam, Xukun Wang, Yong Tan, +8

SLAS DISCOVERY

Divergent roles of GSK3 and CDK5 in APP processing

John Ryder, Su Yuan, Feng Liu, +3

Biochemical and Biophysical Research Communications

App ProcessingEngineeringMobile Operating SystemProgram AnalysisApplication Analysis +1

Regional Distribution, Ontogeny, Purification, and Characterization of the Ca²⁺‐Independent Phospholipase A₂ from Rat Brain

Hsiu‐Chiung Yang, Marian Mosior, Binhui Ni, +1

Journal of Neurochemistry

Proteinlipid InteractionNeurotransmissionLipid MovementCellular NeurobiologySynaptic Signaling +22

α₂‐Macroglobulin as a β‐Amyloid Peptide‐Binding Plasma Protein

Yansheng Du, Binhui Ni, Michele Glinn, +5

Journal of Neurochemistry

Neurodegenerative DiseasesAlzheimer's DiseaseBiochemistryProtein FoldingMedicine +10