Resistance of bulky DNA lesions to nucleotide excision repair can result from extensive aromatic lesion–base stacking interactions

Dara Reeves, Hong Mu, Konstantin Kropachev, +10

Nucleic Acids Research

Dna DamageDna AnalysisMolecular BiologyPathologyMolecular Genetics +15

Nucleotide excision repair of 2-acetylaminofluorene- and 2-aminofluorene-(C8)-guanine adducts: molecular dynamics simulations elucidate how lesion structure and base sequence context impact repair efficiencies

Hong Mu, Konstantin Kropachev, Lihua Wang, +5

Nucleic Acids Research

Structure and mechanism of pyrimidine–pyrimidone (6-4) photoproduct recognition by the Rad4/XPC nucleotide excision repair complex

Debamita Paul, Hong Mu, Hong Zhao, +4

Nucleic Acids Research

Crystal StructureGenome InstabilityPhotoproduct RecognitionNucleic Acid ChemistryPhotochemistry +9

Nucleotide Excision Repair Lesion-Recognition Protein Rad4 Captures a Pre-Flipped Partner Base in a Benzo[<i>a</i>]pyrene-Derived DNA Lesion: How Structure Impacts the Binding Pathway

Hong Mu, Nicholas E. Geacintov, Jung‐Hyun Min, +2

Chemical Research in Toxicology

The relationships between XPC binding to conformationally diverse DNA adducts and their excision by the human NER system: Is there a correlation?

Yuan-Cho Lee, Yuqin Cai, Hong Mu, +5

DNA repair

Natural SciencesGeneticsDna AnalysisMolecular BiologyDna Replication +7

Microsatellite instability and novel mismatch repair gene mutations in northern Chinese population with Hereditary non‐polyposis colorectal cancer

Jian Qiu SHENG, Tsun Leung Chan, Yee Wai Chan, +8

Chinese Journal of Digestive Diseases

Equarin, a novel soluble molecule expressed with polarity at chick embryonic lens equator, is involved in eye formation

Hong Mu, Kunimasa Ohta, Sei Kuriyama, +4

Mechanisms of Development

Developmental BiologyEye FormationOphthalmologyMedicineNovel Soluble Molecule +5

Enhanced spontaneous DNA twisting/bending fluctuations unveiled by fluorescence lifetime distributions promote mismatch recognition by the Rad4 nucleotide excision repair complex

Sagnik Chakraborty, Peter Steinbach, Debamita Paul, +4

Nucleic Acids Research

GeneticsDna AnalysisMolecular BiologyMolecular GeneticsNucleic Acid Biomarkers +14

Recognition of Damaged DNA for Nucleotide Excision Repair: A Correlated Motion Mechanism with a Mismatched <i>cis-syn</i> Thymine Dimer Lesion

Hong Mu, Nicholas E. Geacintov, Yingkai Zhang, +1

Biochemistry

Dna DamageGeneticsDna AnalysisMolecular BiologyMolecular Genetics +18

Lesion Sensing during Initial Binding by Yeast XPC/Rad4: Toward Predicting Resistance to Nucleotide Excision Repair

Hong Mu, Yingkai Zhang, Nicholas E. Geacintov, +1

Chemical Research in Toxicology

Dna LesionsGenome InstabilityNucleic Acid ChemistryYeast Xpc/rad4Medicine +13