Short-term Treatment of RAW264.7 Macrophages with Adiponectin Increases Tumor Necrosis Factor-α (TNF-α) Expression via ERK1/2 Activation and Egr-1 Expression

Pil-Hoon Park, Megan R. McMullen, Honglian Huang, +2

Journal of Biological Chemistry

Immune RegulationImmunologyInflammationMetabolic SyndromeTranscriptional Regulation +17

Adiponectin and Heme Oxygenase-1 Suppress TLR4/MyD88-Independent Signaling in Rat Kupffer Cells and in Mice after Chronic Ethanol Exposure

Palash Mandal, Sanjoy Roychowdhury, Pil-Hoon Park, +3

The Journal of Immunology

Immune RegulationImmunologyFatty Liver DiseaseOxidative StressInflammation +21

Dihydroxylated 2,4,6-triphenyl pyridines: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study

Radha Karki, Han Young Yoo, Tara Man Kadayat, +3

European Journal of Medicinal Chemistry

BiochemistryStructure–activity Relationship StudyMedicineIi Inhibitory ActivityOrganic Chemistry +5

Suppression of Lipopolysaccharide-stimulated Tumor Necrosis Factor-α Production by Adiponectin Is Mediated by Transcriptional and Post-transcriptional Mechanisms

Pil-Hoon Park, Honglian Huang, Megan R. McMullen, +3

Journal of Biological Chemistry

InflammationBiochemistryImmunologyMetabolic SignalingMetabolic Regulation +7

Activation of cyclic-AMP response element binding protein contributes to adiponectin-stimulated interleukin-10 expression in raw 264.7 macrophages

Pil-Hoon Park, Honglian Huang, Megan R. McMullen, +2

Journal of Leukocyte Biology

Hirsutenone reduces deterioration of tight junction proteins through EGFR/Akt and ERK1/2 pathway both converging to HO-1 induction

Geom Seog Seo, Wen-Yi Jiang, Pil-Hoon Park, +3

Biochemical Pharmacology

Signal TransductionSignaling PathwayTight Junction ProteinsHo-1 InductionReceptor Tyrosine Kinase +5

Globular Adiponectin Inhibits Ethanol-Induced Reactive Oxygen Species Production through Modulation of NADPH Oxidase in Macrophages: Involvement of Liver Kinase B1/AMP-Activated Protein Kinase Pathway

Mi Jin Kim, Laura E. Nagy, Pil-Hoon Park

Molecular Pharmacology

Emodin Isolated from Polygoni cuspidati Radix Inhibits TNF-α and IL-6 Release by Blockading NF-κB and MAP Kinase Pathways in Mast Cells Stimulated with PMA Plus A23187

Yue Lu, Yong Tae Jeong, Xian Li, +5

Biomolecules & Therapeutics

Inhibitory effect of putranjivain A on allergic inflammation through suppression of mast cell activation

Hui-Hun Kim, Seung-Bin Park, Soyoung Lee, +5

Toxicology and Applied Pharmacology

AsthmaInflammationCytokineAnti-inflammatoryAllergy +9

Effects of Baicalin on Oral Pharmacokinetics of Caffeine in Rats

Keumhan Noh, Mahesh R. Nepal, Ki Sun Jeong, +8

Biomolecules & Therapeutics

Medicinal ChemistryPolyphenolicsPharmacological StudyBiochemistryMedicine +13