Effect of YC‐1, an NO‐independent, superoxide‐sensitive stimulator of soluble guanylyl cyclase, on smooth muscle responsiveness to nitrovasodilators

Alexander Mülsch, Johann Bauersachs, Andreas Schäfer, +3

British Journal of Pharmacology

Neladenoson Bialanate Hydrochloride: A Prodrug of a Partial Adenosine A₁ Receptor Agonist for the Chronic Treatment of Heart Diseases

Daniel Meibom, Barbara Albrecht‐Küpper, Nicole Diedrichs, +9

ChemMedChem

Design and Synthesis of Potent and Selective Azaindole‐Based Rho Kinase (ROCK) Inhibitors

Hartmut Schirok, Raimund Kast, Santiago Figueroa‐Pérez, +15

ChemMedChem

Molecular DockingMolecular PharmacologyMedicinal ChemistryBioorganic ChemistryAvailable Rock Inhibitor +13

A role for coagulation factor Xa in experimental pulmonary arterial hypertension

Martina Delbeck, Katrin Nickel, Elisabeth Perzborn, +7

Cardiovascular Research

Activation of a keratinocyte phospholipase A₂ by bradykinin and 4β‐phorbol 12‐myristate 13‐acetate

Raimund Kast, Gerhard Fürstenberger, Friedrich Marks

European Journal of Biochemistry

DermatologyLipid MovementCellular PhysiologyOxidative StressInflammation +17

Potent and Selective Human Prostaglandin F (FP) Receptor Antagonist (BAY-6672) for the Treatment of Idiopathic Pulmonary Fibrosis (IPF)

Hartmut Beck, Tobias Thaler, Daniel Meibom, +19

Journal of Medicinal Chemistry

Selective Attenuation of Norepinephrine Release and Stress-Induced Heart Rate Increase by Partial Adenosine A1 Agonism

Lorenz Bott‐Flügel, Alexandra Bernshausen, Heike Schneider, +7

PLoS ONE

Generation and Characterization of a Stable Soluble Guanylate Cyclase-Overexpressing CHO Cell Line

Eva Maria Becker, Frank Wunder, Raimund Kast, +5

Nitric Oxide

BiochemistryNatural SciencesBiochemical GeneticsCellular BiochemistryMedicine +3

Identification and optimization of substituted 5-aminopyrazoles as potent and selective adenosine A1 receptor antagonists

Nils Griebenow, Lars Bärfacker, Heinrich Meier, +5

Bioorganic & Medicinal Chemistry Letters

BiochemistryFunctional SelectivityMedicineMechanism Of ActionSubstituted 5-Aminopyrazoles +4

Novel non-xanthine antagonist of the A2B adenosine receptor: From HTS hit to lead structure

Michael Härter, Bernd Kalthof, Martina Delbeck, +6

European Journal of Medicinal Chemistry

Signal TransductionBiochemistryG Protein-coupled ReceptorNovel Non-xanthine AntagonistMedicine +6