Mucoid Pseudomonas aeruginosa in cystic fibrosis: characterization of muc mutations in clinical isolates and analysis of clearance in a mouse model of respiratory infection

J C Boucher, Hongwei D. Yu, Michal Mudd, +1

Infection and Immunity

Medical MicrobiologyMucoid Pseudomonas AeruginosaAntimicrobial Resistance GeneCf IsolatesPathogenesis +11

Control of AlgU, a member of the sigma E-like family of stress sigma factors, by the negative regulators MucA and MucB and Pseudomonas aeruginosa conversion to mucoidy in cystic fibrosis

Michael J. Schurr, Hongwei D. Yu, J M Martínez-Salazar, +2

Journal of Bacteriology

Sigma ENatural SciencesStress Sigma FactorsPathogenesisBacteriology +13

Two distinct loci affecting conversion to mucoidy in Pseudomonas aeruginosa in cystic fibrosis encode homologs of the serine protease HtrA

J C Boucher, J M Martínez-Salazar, Michael J. Schurr, +3

Journal of Bacteriology

BiochemistryNatural SciencesGeneticsVirulence FactorBacteriology +12

Global Genomic Analysis of AlgU (σ ^E )-Dependent Promoters (Sigmulon) in <i>Pseudomonas aeruginosa</i> and Implications for Inflammatory Processes in Cystic Fibrosis

Aaron M. Firoved, J C Boucher, Vojo Deretić

Journal of Bacteriology

Multiple promoters and induction by heat shock of the gene encoding the alternative sigma factor AlgU (sigma E) which controls mucoidy in cystic fibrosis isolates of Pseudomonas aeruginosa

Michael J. Schurr, Hongwei D. Yu, J C Boucher, +2

Journal of Bacteriology

Environmental StressGeneticsBacteriologyEscherichia ColiExopolysaccharide Alginate +15

Dual regulation of mucoidy in <i>Pseudomonas aeruginosa</i> and sigma factor antagonism

J C Boucher, Michael J. Schurr, Vojo Deretić

Molecular Microbiology

Characterization of the genes coding for the putative sigma factor AlgU and its regulators MucA, MucB, MucC, and MucD in Azotobacter vinelandii and evaluation of their roles in alginate biosynthesis

J M Martínez-Salazar, Silverio Hernández Moreno, Rosa María Sánchez Nájera, +3

Journal of Bacteriology

GeneticsBacteriologyMolecular BiologyMolecular GeneticsPhylogenetic Analysis +14

Molecular basis for defective glycosylation and <i>Pseudomonas</i> pathogenesis in cystic fibrosis lung

Jens F. Poschet, J C Boucher, L. Tatterson, +3

Proceedings of the National Academy of Sciences

Inflammatory Lung DiseaseLung InflammationGlycobiologyMolecular BiologyBacterial Pathogens +19

Microbial Pathogenesis in Cystic Fibrosis: Pulmonary Clearance of Mucoid<i>Pseudomonas aeruginosa</i>and Inflammation in a Mouse Model of Repeated Respiratory Challenge

Hongwei D. Yu, Martha A. Hanes, Clarence E. Chrisp, +2

Infection and Immunity

Pseudomonas aeruginosa in cystic fibrosis: role of mucC in the regulation of alginate production and stress sensitivity

J C Boucher, Michael J. Schurr, Hongwei D. Yu, +2

Microbiology