Prophylaxis and reversal of ifosfamide encephalopathy with methylene-blue

A Küpfer, C. Aeschlimann, B. Wermuth, +1

The Lancet

Cerebrospinal FluidClinical PharmacologyToxicologyPharmacotherapyNeurology +2

Methylene blue and the neurotoxic mechanisms of ifosfamide encephalopathy

A Küpfer, C. Aeschlimann, T. Cerny

European Journal of Clinical Pharmacology

MedicineMethylene BlueNeuropharmacologyToxicologyNeuroprotection +4

Assessment of P-glycoprotein, glutathione-based detoxifying enzymes and O6-alkylguanine-DNA alkyltransferase as potential indicators of constitutive drug resistance in human colorectal tumors.

Shelagh Redmond, Franziska Joncourt, K Buser, +5

PubMed

Constitutive Drug ResistanceTumor BiologyHealth SciencesPotential IndicatorsMedicine +12

Prolongation of ifosfamide elimination half-life in obese patients due to altered drug distribution

Michael Lind, J. Margison, T. Cerny, +2

Cancer Chemotherapy and Pharmacology

ObesityMetabolic SyndromeBariatric SurgeryDiabetesPharmacology +7

Elevated preoperative CEA is associated with worse survival in stage I–III rectal cancer patients

Ignazio Tarantino, René Warschkow, Mathias Worni, +7

British Journal of Cancer

Cladribine (2‐CDA) given as subcutaneous bolus injections is active in pretreated Waldenström's macroglobulinaemia

Daniel Betticher, S.‐F. Hsu Schmitz, Daniel Ratschiller, +7

British Journal of Haematology

Metabolism and pharmacokinetics of oral and intravenous ifosfamide

Volkhard Kurowski, T. Cerny, A Küpfer, +1

Journal of Cancer Research and Clinical Oncology

Pharmacological StudyPharmacologyPharmacotherapyMetabolismMedicine +2

Thiodiglycolic acid is excreted by humans receiving ifosfamide and inhibits mitochondrial function in rats.

Theresa Visarius, Hanna Bähler, A Küpfer, +2

PubMed

Pharmaceutical ScienceChemoprevention StrategyLipid PeroxidationCell DeathIfosfamide Infusion +19

Saturable metabolism of continuous high-dose ifosfamide with Mesna and GM-CSF: A pharmacokinetic study in advanced sarcoma patients

T. Cerny, Serge Leyvraz, Thomas von Briel, +7

Annals of Oncology

Advanced Sarcoma PatientsContinuous High-dose IfosfamideMedicineMetronomic TherapyPharmacology +5

A simple outpatient treatment with oral Ifosfamide and oral Etoposide for patients with small cell lung cancer (SCLC)

T. Cerny, Michael Lind, N. Thatcher, +2

British Journal of Cancer

OncologyCancer ManagementOral EtoposidePharmacotherapyCancer Treatment +6