Plaque assay and primary isolation of influenza a viruses in an established line of canine kidney cells (MDCK) in the presence of trypsin

K. Tobita, Akira Sugiura, C. Enomoto, +1

Medical Microbiology and Immunology

Plaque AssayViral DiagnosticsMedicineViral PathogenesisImmunology +5

Isolation and Preliminary Characterization of Temperature-Sensitive Mutants of Influenza Virus

Akira Sugiura, K. Tobita, Edwin D. Kilbourne

Journal of Virology

Viral ReplicationReverse GeneticsGeneticsMolecular BiologyMolecular Genetics +14

Permanent canine kidney (MDCK) cells for isolation and plaque assay of influenza B viruses

K. Tobita

Medical Microbiology and Immunology

Plaque AssayDiagnostic VirologyViral DiagnosticsViral PathogenesisImmunology +4

Homologous interference mediated by defective interfering influenza virus derived from a temperature-sensitive mutant of influenza virus

Debi P. Nayak, K. Tobita, J Janda, +2

Journal of Virology

Virus StructureViral ReplicationViral EvolutionMolecular VirologyTemperature-sensitive Mutant +11

Tryptase Clara, an activating protease for Sendai virus in rat lungs, is involved in pneumopathogenicity

Masato Tashiro, Yutaka Yokogoshi, K. Tobita, +3

Journal of Virology

Inflammatory Lung DiseaseImmunologyViral PathogenesisImmunodominanceTryptase Clara +14

Further isolation and characterization of temperature-sensitive mutants of influenza virus

Akira Sugiura, Masahiro Ueda, K. Tobita, +1

Virology

Virus StructurePathogenesisVirologyInfluenza VaccineMicrobiology +2

Mutation in NS2, a nonstructural protein of influenza A virus, extragenically causes aberrant replication and expression of the PA gene and leads to generation of defective interfering particles.

Takato Odagiri, K. Tobita

Proceedings of the National Academy of Sciences

Viral ReplicationViral EvolutionDefective Interfering ParticlesGeneticsPathogenesis +10

Altered budding site of a pantropic mutant of Sendai virus, F1-R, in polarized epithelial cells

Masato Tashiro, Makoto Yamakawa, K. Tobita, +3

Journal of Virology

Viral ReplicationViral PathogenesisImmunologyPathologyVirus Structure +14

Organ tropism of Sendai virus in mice: proteolytic activation of the fusion glycoprotein in mouse organs and budding site at the bronchial epithelium

Masato Tashiro, Makoto Yamakawa, K. Tobita, +3

Journal of Virology

Viral ReplicationMolecular VirologySynthetic VirologyMedicinePathogenesis +13

Genetic Recombination for Antigenic Markers of Antigenically Different Strains of Influenza B Virus

K. Tobita, Edwin D. Kilbourne

Journal of Virology

Reverse GeneticsSynthetic VirologyImmunologyStrain SelectionViral Structural Protein +14