A fetal systemic inflammatory response is followed by the spontaneous onset of preterm parturition

Roberto Romero, Ricardo Gómez, Fabio Ghezzi, +4

American Journal of Obstetrics and Gynecology

InflammationDevelopmental BiologyAutoimmune DiseasePreterm LaborImmunology +12

Evidence supporting a role for blockade of the vascular endothelial growth factor system in the pathophysiology of preeclampsia

Tinnakorn Chaiworapongsa, Roberto Romero, Jimmy Espinoza, +5

American Journal of Obstetrics and Gynecology

HypertensionCardiovascular DiseaseMaternal Cardiovascular OutcomeGestational HypertensionPhysiology +10

Plasma soluble vascular endothelial growth factor receptor-1 concentration is elevated prior to the clinical diagnosis of pre-eclampsia

Tinnakorn Chaiworapongsa, Roberto Romero, Yeon Mee Kim, +8

The Journal of Maternal-Fetal & Neonatal Medicine

The change in concentrations of angiogenic and anti-angiogenic factors in maternal plasma between the first and second trimesters in risk assessment for the subsequent development of preeclampsia and small-for-gestational age

Offer Erez, Roberto Romero, Jimmy Espinoza, +12

The Journal of Maternal-Fetal & Neonatal Medicine

A prospective cohort study of the value of maternal plasma concentrations of angiogenic and anti-angiogenic factors in early pregnancy and midtrimester in the identification of patients destined to develop preeclampsia

Juan Pedro Kusanovic, Roberto Romero, Tinnakorn Chaiworapongsa, +10

The Journal of Maternal-Fetal & Neonatal Medicine

Interleukin-6 stimulates prostaglandin production by human amnion and decidual cells

Murray D. Mitchell, Donald J. Dudley, Samuel S. Edwin, +1

European Journal of Pharmacology

InflammationCytokineAutoimmune DiseaseImmune Cell DevelopmentImmunology +5

A role for matrix metalloproteinase-9 in spontaneous rupture of the fetal membranes

Neil Athayde, Samuel S. Edwin, Roberto Romero, +4

American Journal of Obstetrics and Gynecology

Developmental BiologyPlacental DevelopmentMetalloproteinPathologySpontaneous Rupture +8

Normal pregnancy is characterized by systemic activation of the complement system

Karina Richani, Eleazar Soto, Roberto Romero, +7

The Journal of Maternal-Fetal & Neonatal Medicine

Elevated interleukin-8 concentrations in amniotic fluid of mothers whose neonates subsequently develop bronchopulmonary dysplasia

Fabio Ghezzi, Ricardo Gómez, Roberto Romero, +5

European Journal of Obstetrics & Gynecology and Reproductive Biology

InflammationMaternal ImmunizationAmniotic FluidBronchopulmonary DysplasiaLung Inflammation +7

Evidence of in vivo differential bioavailability of the active forms of matrix metalloproteinases 9 and 2 in parturition, spontaneous rupture of membranes, and intra-amniotic infection

Eli Maymon, Roberto Romero, Percy Pacora, +4

American Journal of Obstetrics and Gynecology

BiochemistryMetalloproteinPathogenesisImmunologySpontaneous Rupture +5