J.R. Kiechel

Fluoronaphthyridines and quinolones as antibacterial agents. 2. Synthesis and structure-activity relationships of new 1-tert-butyl 7-substituted derivatives

D. Bouzard, P. DI CESARE, M. ESSIZ et al. · Journal of Medicinal Chemistry · 1990 · 79 citations

Antibacterial Agents, Organic Chemistry, Antimicrobial Chemotherapy +17

Species differences in metabolism of ketotifen in rat, rabbit and man: Demonstration of similar pathways and in cultured hepatocytes

J. F. Le Bigot, Jean M. Bégué, J.R. Kiechel et al. · Life Sciences · 1987 · 78 citations

Cultured Hepatocytes, Pharmacological Study, Biochemistry +12

Cultured human adult hepatocytes: a new model for drug metabolism studies

Jean M. Bégué, J. F. Le Bigot, Christiane Guguen‐Guillouzo et al. · Biochemical Pharmacology · 1983 · 69 citations

Hepatology, Biochemistry, Drug Metabolism Studies +13

The efficacy and safety of a new fixed-dose combination of amodiaquine and artesunate in young African children with acute uncomplicated Plasmodium falciparum

Sodiomon B. Sirima, Alfred B. Tiono, Adama Gansané et al. · Malaria Journal · 2009 · 60 citations · Full text

Effect of the binding of isradipine and darodipine to different plasma proteins on their transfer through the rat blood-brain barrier. Drug binding to lipoproteins does not limit the transfer of drug.

Saı̈k Urien, J.L. Pinquier, Benoît Paquette et al. · Journal of Pharmacology and Experimental Therapeutics · 1987 · 46 citations