Shân L. Gyles

Prostaglandin D2 Causes Preferential Induction of Proinflammatory Th2 Cytokine Production through an Action on Chemoattractant Receptor-Like Molecule Expressed on Th2 Cells

Luzheng Xue, Shân L. Gyles, Frank R. Wettey et al. · The Journal of Immunology · 2005 · 263 citations

Asthma, Inflammatory Lung Disease, Lung Inflammation +19

ERKs Regulate Cyclic AMP-induced Steroid Synthesis through Transcription of the Steroidogenic Acute Regulatory (StAR) Gene

Shân L. Gyles, Chris Burns, Barbara J. Whitehouse et al. · Journal of Biological Chemistry · 2001 · 178 citations · Full text

A dominant role for chemoattractant receptor‐homologous molecule expressed on T helper type 2 (Th2) cells (CRTH2) in mediating chemotaxis of CRTH2⁺ CD4⁺ Th2 lymphocytes in response to mast cell supernatants

Shân L. Gyles, Luzheng Xue, Elizabeth Townsend et al. · Immunology · 2006 · 48 citations · Full text

Mast Cell Disorder, Immunology, Immune Regulation +25

Indole-3-acetic Acid Antagonists of the Prostaglandin D₂ Receptor CRTH2

Richard Armer, Mark Ashton, Edward A. Boyd et al. · Journal of Medicinal Chemistry · 2005 · 48 citations · Full text

Indole-3-acetic Acid Antagonists, Crth2 Receptor, Immunology +21

Δ12-Prostaglandin D2 is a potent and selective CRTH2 receptor agonist and causes activation of human eosinophils and Th2 lymphocytes

Lucien Gazi, Shân L. Gyles, Jennifer Rose et al. · Prostaglandins & Other Lipid Mediators · 2005 · 46 citations

Cytokine, Signal Transduction, Molecular Physiology +10