Paula N. Friedman

Identification of p53 as a Sequence-Specific DNA-Binding Protein

Scott E. Kern, Kenneth W. Kinzler, Arthur M. Bruskin et al. · Science · 1991 · 1.1K citations

Cancer Research, Oncogenic Agent, Natural Sciences +12

Wild-type p53 activates transcription in vitro

George E. Farmer, Jill Bargonetti, Hua Zhu et al. · Nature · 1992 · 591 citations

Transcriptional Regulation, Tumor Suppressor, Gene Expression +2

Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication

Jill Bargonetti, Paula N. Friedman, Scott E. Kern et al. · Cell · 1991 · 380 citations

Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2.

James R. Bischoff, Paula N. Friedman, D R Marshak et al. · Proceedings of the National Academy of Sciences · 1990 · 351 citations · Full text

Primary Site, Tumor Biology, Cell Regulation +10

The p53 protein is an unusually shaped tetramer that binds directly to DNA.

Paula N. Friedman, Xiaohong Chen, Jill Bargonetti et al. · Proceedings of the National Academy of Sciences · 1993 · 258 citations

Chromatin, Wild-type P53, Nucleic Acid Chemistry +14