Joren De Raeymaecker

Pharmacophore modeling: advances, limitations, and current utility in drug discovery

Arnout Voet, Xiao‐Yu Qing, Xiao Yin Lee et al. · Journal of Receptor Ligand and Channel Research · 2014 · 135 citations · Full text

Drug Target, Engineering, Systems Pharmacology +21

In silico, in vitro and cellular analysis with a kinome-wide inhibitor panel correlates cellular LRRK2 dephosphorylation to inhibitor activity on LRRK2

Renée Vancraenenbroeck, Joren De Raeymaecker, Evy Lobbestael et al. · Frontiers in Molecular Neuroscience · 2014 · 57 citations · Full text

Kinome-wide Inhibitor Panel, Cellular Analysis, Kinase Inhibitors +17

Structures of the heart specific <scp>SERCA</scp> 2a Ca ²⁺ ‐ <scp>ATP</scp> ase

Aljona Sitsel, Joren De Raeymaecker, N.D. Drachmann et al. · The EMBO Journal · 2019 · 54 citations · Full text

Structure/activity relationship of thapsigargin inhibition on the purified Golgi/secretory pathway Ca2+/Mn2+-transport ATPase (SPCA1a)

Jialin Chen, Joren De Raeymaecker, Jannik Brøndsted Hovgaard et al. · Journal of Biological Chemistry · 2017 · 22 citations · Full text

The novel ADAMTS13‐p.D187H mutation impairs ADAMTS13 activity and secretion and contributes to thrombotic thrombocytopenic purpura in mice

Elien De Cock, Cédric Hermans, Joren De Raeymaecker et al. · Journal of Thrombosis and Haemostasis · 2014 · 19 citations · Full text