Mammen O Anup

Treatment with CNX-011-67, a novel GPR40 agonist, delays onset and progression of diabetes and improves beta cell preservation and function in male ZDF rats

Nagesh Gowda, Anilkumar Dandu, Jaideep Singh et al. · BMC Pharmacology and Toxicology · 2013 · 26 citations · Full text

Medicine, Endocrinology, Pharmacology +17

A novel 11β-hydroxysteroid dehydrogenase type1 inhibitor CNX-010-49 improves hyperglycemia, lipid profile and reduces body weight in diet induced obese C57B6/J mice with a potential to provide cardio protective benefits

Anil Mathew Tharappel, Anilkumar Dandu, KrishnaReddy Harsha et al. · BMC Pharmacology and Toxicology · 2014 · 19 citations · Full text

Life Sciences, Endocrinology, Pharmacology +17

CNX-012-570, a direct AMPK activator provides strong glycemic and lipid control along with significant reduction in body weight; studies from both diet-induced obese mice and db/db mice models

Anil Mathew Tharappel, C. Harish, Mudigere N Lakshmi et al. · Cardiovascular Diabetology · 2014 · 16 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

CNX-013-B2, a unique pan tissue acting rexinoid, modulates several nuclear receptors and controls multiple risk factors of the metabolic syndrome without risk of hypertriglyceridemia, hepatomegaly and body weight gain in animal models

Manoj Kumar Sadasivuni, Bobbili Madhusudhan Reddy, Jaideep Singh et al. · Diabetology & Metabolic Syndrome · 2014 · 10 citations · Full text

Medicine, Endocrinology, Pharmacology +17