Mudigere N Lakshmi

Treatment with CNX-011-67, a novel GPR40 agonist, delays onset and progression of diabetes and improves beta cell preservation and function in male ZDF rats

Nagesh Gowda, Anilkumar Dandu, Jaideep Singh et al. · BMC Pharmacology and Toxicology · 2013 · 26 citations · Full text

A novel 11β-hydroxysteroid dehydrogenase type1 inhibitor CNX-010-49 improves hyperglycemia, lipid profile and reduces body weight in diet induced obese C57B6/J mice with a potential to provide cardio protective benefits

Anil Mathew Tharappel, Anilkumar Dandu, KrishnaReddy Harsha et al. · BMC Pharmacology and Toxicology · 2014 · 18 citations · Full text

Inhibition of neutral sphingomyelinases in skeletal muscle attenuates fatty-acid induced defects in metabolism and stress

Mahesh Kumar Verma, Aggunda Nagaraju Yateesh, Korrapati Neelima et al. · SpringerPlus · 2014 · 16 citations · Full text

CNX-012-570, a direct AMPK activator provides strong glycemic and lipid control along with significant reduction in body weight; studies from both diet-induced obese mice and db/db mice models

Anil Mathew Tharappel, C. Harish, Mudigere N Lakshmi et al. · Cardiovascular Diabetology · 2014 · 16 citations · Full text

CNX-013-B2, a unique pan tissue acting rexinoid, modulates several nuclear receptors and controls multiple risk factors of the metabolic syndrome without risk of hypertriglyceridemia, hepatomegaly and body weight gain in animal models

Manoj Kumar Sadasivuni, Bobbili Madhusudhan Reddy, Jaideep Singh et al. · Diabetology & Metabolic Syndrome · 2014 · 10 citations · Full text