Kenneth R. Harrap

Early clinical studies with cis-diammine-1,1-cyclobutane dicarboxylate platinum II

A. Hilary Calvert, S.J. Harland, David R. Newell et al. · Cancer Chemotherapy and Pharmacology · 1982 · 485 citations

Oncology, Medicine, Clinical Studies +4

Preclinical studies identifying carboplatin as a viable cisplatin alternative

Kenneth R. Harrap · Cancer Treatment Reviews · 1985 · 253 citations

Chromatin, Medicine, Viable Cisplatin Alternative +5

Pharmacokinetics of cis-diammine-1,1-cyclobutane dicarboxylate platinum(II) in patients with normal and impaired renal function.

S.J. Harland, David R. Newell, Zahid H. Siddik et al. · PubMed · 1984 · 247 citations

Cis-diammine-1,1-cyclobutane Dicarboxylate Platinum, Pharmacotherapy, Free Platinum +17

Preclinical antitumor evaluation of bis-acetato-ammine-dichloro-cyclohexylamine platinum(IV): an orally active platinum drug.

Lloyd R. Kelland, G Abel, Mark J. McKeage et al. · PubMed · 1993 · 224 citations

Chemoprevention Strategy, Active Platinum Drug, Pathology +18

Ammine/amine platinum(IV) dicarboxylates: a novel class of platinum complex exhibiting selective cytotoxicity to intrinsically cisplatin-resistant human ovarian carcinoma cell lines.

Lloyd R. Kelland, Barry A. Murrer, G Abel et al. · PubMed · 1992 · 168 citations

Chemoprevention Strategy, Cisplatin-resistant Cell Lines, Selective Cytotoxicity +16