James S. Felton

High concentrations of the carcinogen 2-amino-1-methyl-6-phenylimidazo- [4,5-b]pyridine (PhIP) occur in chicken but are dependent on the cooking method.

Rashmi Sinha, Nathaniel Rothman, Ellen Brown et al. · PubMed · 1995 · 272 citations

Agriculture, Food Science, Poultry Science +11

Ontogenetic expression of polycyclic aromatic compound-inducible monooxygenase activities and forms of cytochrome P-450 in rabbit. Evidence for temporal control and organ specificity of two genetic regulatory systems.

Steven A. Atlas, Alan R. Boobis, James S. Felton et al. · Journal of Biological Chemistry · 1977 · 164 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

Comparison of beta-naphthoflavone and 3-methylcholanthrene as inducers of hepatic cytochrome(s) P-448 and aryl hydrocarbon (benzo[a]pyrene) hydroxylase activity.

Alan R. Boobis, Daniel W. Nebert, James S. Felton · PubMed · 1977 · 120 citations

Medicine, Biochemistry, Pharmacology +14

Species differences in the substrate specificity of hepatic cytochrome P-448 From polycyclic hydrocarbon-treated animals

Snorri S. Thorgeirsson, Steven A. Atlas, Alan R. Boobis et al. · Biochemical Pharmacology · 1979 · 84 citations

Medicine, Biochemistry, Pharmacology +16

Mutagenesis of certain activated carcinogens in vitro associated with genetically mediated increases in monooxygenase activity and cytochrome P 1-450.

James S. Felton, D W Nebert · Journal of Biological Chemistry · 1975 · 83 citations · Full text

Medicine, Biochemistry, Toxicology +17