P F Searle

In vivo gene therapy for colon cancer using adenovirus-mediated, transfer of the fusion gene cytosine deaminase and uracil phosphoribosyltransferase

GA Chung-Faye, Green Nk, Andrea Burton et al. · Gene Therapy · 2001 · 87 citations

Vivo Gene Therapy, Medicine, Colorectal Cancer +7

Strategies for the isolation and purification of retroviral vectors for gene therapy.

Geneviève M.F Braas, P F Searle, N K Slater et al. · PubMed · 1996 · 73 citations

Virus-directed enzyme prodrug therapy using CB1954.

Jane I. Grove, P F Searle, Sarah J. Weedon et al. · PubMed · 1999 · 54 citations

Ntr Delivery, Medicine, Converts Cb1954 +12

Enhanced efficacy of Escherichia coli nitroreductase/CB1954 prodrug activation gene therapy using an E1B-55K-deleted oncolytic adenovirus vector

Mei‐Jou Chen, N K Green, G M Reynolds et al. · Gene Therapy · 2004 · 43 citations

Gene Therapies, Enhanced Efficacy, Biological Therapy +7

Direct positive selection for improved nitroreductase variants using SOS triggering of bacteriophage lambda lytic cycle

Christopher P. Guise, Jane I. Grove, Eva I. Hyde et al. · Gene Therapy · 2007 · 34 citations

Improved Nitroreductase Variants, Sos Triggering, Bacteriophage +5