P F Searle

In vivo gene therapy for colon cancer using adenovirus-mediated, transfer of the fusion gene cytosine deaminase and uracil phosphoribosyltransferase

GA Chung-Faye, Green Nk, Andrea Burton et al. · Gene Therapy · 2001 · 87 citations

Medicine, Molecular Biology, Oncology +17

Strategies for the isolation and purification of retroviral vectors for gene therapy.

Geneviève M.F Braas, P F Searle, N K Slater et al. · PubMed · 1996 · 73 citations

Life Sciences, Biotechnology, Molecular Biology +14

Virus-directed enzyme prodrug therapy using CB1954.

Jane I. Grove, P F Searle, Sarah J. Weedon et al. · PubMed · 1999 · 54 citations

Pharmacy, Oncology, Pharmacology +13

Enhanced efficacy of Escherichia coli nitroreductase/CB1954 prodrug activation gene therapy using an E1B-55K-deleted oncolytic adenovirus vector

N K Green, G M Reynolds, J R Flavell et al. · Gene Therapy · 2004 · 44 citations

Medicine, Biotechnology, Oncology +13

Direct positive selection for improved nitroreductase variants using SOS triggering of bacteriophage lambda lytic cycle

Christopher P. Guise, Jane I. Grove, Eva I. Hyde et al. · Gene Therapy · 2007 · 38 citations

Life Sciences, Biotechnology, Microbiology +17