T. Bruin

A missense mutation at codon 188 of the human lipoprotein lipase gene is a frequent cause of lipoprotein lipase deficiency in persons of different ancestries.

María Victoria Monsalve, Heather Henderson, Ghislaine O. Roederer et al. · Journal of Clinical Investigation · 1990 · 169 citations · Full text

Lipoprotein Lipase, Genetics, Genetic Epidemiology +19

The Asp ₉ Asn Mutation in the Lipoprotein Lipase Gene Is Associated With Increased Progression of Coronary Atherosclerosis

J. Wouter Jukema, Ad J. van Boven, Bjo ̈rn Groenemeijer et al. · Circulation · 1996 · 123 citations

Two naturally occurring mutations at the first and second bases of codon aspartic acid 156 in the proposed catalytic triad of human lipoprotein lipase. In vivo evidence that aspartic acid 156 is essential for catalysis.

Y H, T. Bruin, S. Tuzgöl et al. · Journal of Biological Chemistry · 1992 · 43 citations · Full text

Antithrombin III metabolism in two colitis patients with acquired antithrombin III deficiency

E.A.R. Knot, J W ten Cate, T. Bruin et al. · Gastroenterology · 1985 · 29 citations

Inflammation, Autoimmune Disease, Antithrombin Iii Metabolism +8

A compound heterozygote for lipoprotein lipase deficiency, Val69–>Leu and Gly188–>Glu: correlation between in vitro LPL activity and clinical expression.

T. Bruin, S. Tuzgöl, Willem J. M. Mulder et al. · Journal of Lipid Research · 1994 · 18 citations · Full text

Lipid Analysis, Metabolic Syndrome, Lipoprotein Lipase Deficiency +14