Y Uehara

Phenotypic change from transformed to normal induced by benzoquinonoid ansamycins accompanies inactivation of p60src in rat kidney cells infected with Rous sarcoma virus.

Y Uehara, MAKOTO HORI, TOMIO TAKEUCHI et al. · Molecular and Cellular Biology · 1986 · 141 citations

Life Sciences, Cell Biology, Microbiology +9

Mechanism of reversion of Rous sarcoma virus transformation by herbimycin A: reduction of total phosphotyrosine levels due to reduced kinase activity and increased turnover of p60v-src1.

Y Uehara, Yuko Murakami, Y. Sugimoto et al. · PubMed · 1989 · 122 citations

Life Sciences, Biochemistry, Cell Biology +10

A Microplate Assay for Quantitation of Anchorage-Independent Growth of Transformed Cells

H Fukazawa, Satoshi Mizuno, Y Uehara · Analytical Biochemistry · 1995 · 111 citations

Life Sciences, Cell Biology, Molecular Biology +12

Tyrosine phosphorylation provides an early and requisite signal for the activation of natural killer cell cytotoxic function.

K J Einspahr, Robert T. Abraham, Bryce A. Binstadt et al. · Proceedings of the National Academy of Sciences · 1991 · 93 citations

Life Sciences, Cell Biology, Immunology +16

Herbimycin A, a pp60c-src tyrosine kinase inhibitor, inhibits osteoclastic bone resorption in vitro and hypercalcemia in vivo.

Toshiyuki Yoneda, Carolyn Lowe, Chul‐Ho Lee et al. · Journal of Clinical Investigation · 1993 · 89 citations · Full text

Medicine, Pharmacology, Biochemical Pharmacology +16