K. Patel

Phase I/II study to assess safety, pharmacokinetics, and efficacy of the oral MEK 1/2 inhibitor GSK1120212 (GSK212) dosed in combination with the oral BRAF inhibitor GSK2118436 (GSK436).

J. R. Infante, G. S. Falchook, Donald P. Lawrence et al. · Journal of Clinical Oncology · 2011 · 122 citations

Medicine, Oncology, Pharmacology +17

Co-agonist of glucagon and GLP-1 reduces cholesterol and improves insulin sensitivity independent of its effect on appetite and body weight in diet-induced obese C57 mice

Vishal Patel, Amit Joharapurkar, Nirav Dhanesha et al. · Canadian Journal of Physiology and Pharmacology · 2013 · 31 citations

Life Sciences, Endocrinology, Pharmacology +17

Pharmacological Characterization of ZYAN1, a Novel Prolyl Hydroxylase Inhibitor for the Treatment of Anemia

Mukul R. Jain, Amit Joharapurkar, Vrajesh B. Pandya et al. · Drug Research · 2015 · 27 citations

Medicine, Hematology, Pharmacology +13

Treatment with exendin-4 improves the antidiabetic efficacy and reverses hepatic steatosis in glucokinase activator treated db/db mice

Nirav Dhanesha, Amit Joharapurkar, Gaurang Shah et al. · European Journal of Pharmacology · 2013 · 22 citations

Medicine, Biochemistry, Endocrinology +16