J. Thorburn

Autophagy regulates selective HMGB1 release in tumor cells that are destined to die

J. Thorburn, Henrick Horita, Jasmina S. Redzic et al. · Cell Death and Differentiation · 2008 · 268 citations · Full text

Cancer Research, Mitophagy, Cell Autophagy +13

HRas-dependent pathways can activate morphological and genetic markers of cardiac muscle cell hypertrophy.

Andrew Thorburn, J. Thorburn, S.Y. Chen et al. · Journal of Biological Chemistry · 1993 · 229 citations · Full text

Cardiac Muscle, Activated Ras, Cardiac Progenitor Cells +21

Mitogen-activated protein kinases mediate changes in gene expression, but not cytoskeletal organization associated with cardiac muscle cell hypertrophy.

J. Thorburn, Jeffrey A. Frost, Andrew Thorburn · The Journal of Cell Biology · 1994 · 201 citations · Full text

Cardiac Muscle, Signal Transduction Pathways, Cardiovascular Function +18

Gq- and ras-dependent pathways mediate hypertrophy of neonatal rat ventricular myocytes following alpha 1-adrenergic stimulation.

Vickie J. LaMorte, J. Thorburn, Devin Absher et al. · Journal of Biological Chemistry · 1994 · 190 citations · Full text

Raf-1 kinase activity is necessary and sufficient for gene expression changes but not sufficient for cellular morphology changes associated with cardiac myocyte hypertrophy.

J. Thorburn, Martin McMahon, Andrew Thorburn · Journal of Biological Chemistry · 1994 · 109 citations · Full text

Cardiac Muscle, Engineering, Raf-1 Kinase Activity +19