Aida Abu‐Baker

Sirtuin inhibition protects from the polyalanine muscular dystrophy protein PABPN1

Hélène Catoire, Matthieu Y. Pasco, Aida Abu‐Baker et al. · Human Molecular Genetics · 2008 · 61 citations

Molecular Regulation, Apoptosis, Molecular Biology +18

Soluble expanded PABPN1 promotes cell death in oculopharyngeal muscular dystrophy

Christiane Messaed, Patrick A. Dion, Aida Abu‐Baker et al. · Neurobiology of Disease · 2007 · 42 citations · Full text

Pabpn1 Promotes, Cell Signaling, Natural Sciences +12

Automated design of hammerhead ribozymes and validation by targeting the PABPN1 gene transcript

Nawwaf Kharma, Luc Varin, Aida Abu‐Baker et al. · Nucleic Acids Research · 2015 · 28 citations · Full text

Hammerhead Ribozymes, Engineering, Structural Bioinformatics +21

Cytoplasmic Targeting of Mutant Poly(A)‐Binding Protein Nuclear 1 Suppresses Protein Aggregation and Toxicity in Oculopharyngeal Muscular Dystrophy

Aida Abu‐Baker, Simon Laganiere, Xueping Fan et al. · Traffic · 2005 · 20 citations · Full text

Cytoplasmic Targeting, Molecular Biology, Cytoskeleton +18

RNA-Based Therapy Utilizing Oculopharyngeal Muscular Dystrophy Transcript Knockdown and Replacement

Aida Abu‐Baker, Nawwaf Kharma, Jonathan Perreault et al. · Molecular Therapy — Nucleic Acids · 2019 · 20 citations · Full text