Loss of metabolic fitness drives tumor resistance after CAR-NK cell therapy and can be overcome by cytokine engineering

Li Li, Vakul Mohanty, Jinzhuang Dou, +27

Science Advances

ImmunologyNk CellsCar-nk Cell TherapyImmunologic MechanismMetabolic Remodeling +16

Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL

Praveen Anand, Amy Guillaumet-Adkins, Valeriya Dimitrova, +24

Blood

Genomic discovery and clonal tracking in multiple myeloma by cell-free DNA sequencing

Guangwu Guo, Noopur Raje, Charles Seifer, +22

Leukemia

Hematological MalignancyOncologyClonal TrackingTumor HeterogeneityMedicine +10

Dynamic transcriptional reprogramming leads to immunotherapeutic vulnerabilities in myeloma

Julia Frede, Praveen Anand, Noori Sotudeh, +17

Nature Cell Biology

Hematological MalignancyImmunotherapeutic VulnerabilitiesImmunologyMyelopoiesisImmunotherapy +2

A phase II trial of all-trans retinoic acid (ATRA) in advanced adenoid cystic carcinoma

Glenn J. Hanna, Anne O’Neill, Jennifer M. Cutler, +12

Oral Oncology

Tumor BiologyPhase Ii TrialOncogenic AgentMedicinePathology +6

Single-Cell Profiling Reveals Metabolic Reprogramming as a Resistance Mechanism in <i>BRAF</i> -Mutated Multiple Myeloma

Johannes M. Waldschmidt, Jake A. Kloeber, Praveen Anand, +21

Clinical Cancer Research

The modulatory role of phloretin in Aβ25–35 induced sporadic Alzheimer’s disease in rat model

Priya Ghumatkar, Sachin Patil, Vaibhavi Peshattiwar, +4

Naunyn-Schmiedeberg s Archives of Pharmacology

Neurodegenerative DiseasesAlzheimer's DiseaseSynaptic SignalingMedicineNeuropharmacology +10

Cell-free DNA for the detection of emerging treatment failure in relapsed/ refractory multiple myeloma

Johannes M. Waldschmidt, Andrew J. Yee, Tushara Vijaykumar, +25

Leukemia

Hematological MalignancyMedicinePathologyTreatment FailureCell Biology +6

Identification of deubiquitinase targets of isothiocyanates using SILAC-assisted quantitative mass spectrometry

Ann P. Lawson, Daniel W. Bak, David A. Shannon, +6

Oncotarget

Chemoprevention StrategyMolecular BiologyTumor BiologyGas ChromatographyBioanalysis +19

Bisphenol A-induced ultrastructural changes in the testes of common marmoset

Tushara Vijaykumar, Dipty Singh, Geeta Vanage, +2

The Indian Journal of Medical Research