John R. Sadler

A perfectly symmetric lac operator binds the lac repressor very tightly.

John R. Sadler, Henri Sasmor, Joan L. Betz · Proceedings of the National Academy of Sciences · 1983 · 264 citations · Full text

Genetics, Molecular Biology, Molecular Genetics +16

The properties of repressor and the kinetics of its action

John R. Sadler, Aaron Novick · Journal of Molecular Biology · 1965 · 256 citations

Engineering, Mechanics, Equilibrium Thermodynamics +7

Plasmids containing many tandem copies of a synthetic lactose operator

John R. Sadler, Marianne Tecklenburg, Joan L. Betz · Gene · 1980 · 143 citations

Biosynthesis, Engineering, Synthetic Lactose Operator +5

The nature of Lactose operator constitutive mutations

Temple F. Smith, John R. Sadler · Journal of Molecular Biology · 1971 · 142 citations

Biosynthesis, Cellular Enzymology, Genetics +5

Statistical characterization of nucleic acid sequence functional domains

Temple F. Smith, Michael S. Waterman, John R. Sadler · Nucleic Acids Research · 1983 · 101 citations · Full text