Mie Fabricius Pedersen

Structural insights into differences in G protein activation by family A and family B GPCRs

Daniel Hilger, Kaavya Krishna Kumar, Hongli Hu et al. · Science · 2020 · 154 citations · Full text

Human GIP(3-30)NH2 inhibits G protein-dependent as well as G protein-independent signaling and is selective for the GIP receptor with high-affinity binding to primate but not rodent GIP receptors

M Gabe, Alexander H. Sparre‐Ulrich, Mie Fabricius Pedersen et al. · Biochemical Pharmacology · 2018 · 100 citations

Rodent Gip Receptors, Molecular Physiology, Signal Transduction +11

Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics

Mie Fabricius Pedersen, Tomasz M. Wróbel, Emil Märcher-Rørsted et al. · Neuropharmacology · 2019 · 78 citations · Full text

Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells

Thor C. Møller, Mie Fabricius Pedersen, Jeffrey R. van Senten et al. · Scientific Reports · 2020 · 54 citations · Full text

Cellular Physiology, Molecular Pharmacology, Signaling Pathway +16

Characterization of the real-time internalization of nine GPCRs reveals distinct dependence on arrestins and G proteins

Thor C. Møller, Ee Von Moo, Asuka Inoue et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2023 · 15 citations · Full text

Molecular Biology, Real-time Internalization, Cellular Physiology +19