Alex Penson

Therapeutic Targeting of RNA Splicing Catalysis through Inhibition of Protein Arginine Methylation

Jia Yi Fong, Luca Pignata, Pierre-Alexis Goy et al. · Cancer Cell · 2019 · 279 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +16

Spliceosomal disruption of the non-canonical BAF complex in cancer

Daichi Inoue, Guo-Liang Chew, Bo Liu et al. · Nature · 2019 · 241 citations

Medicine, Cancer Biology, Molecular Biology +10

Pervasive mutations of JAK-STAT pathway genes in classical Hodgkin lymphoma

Enrico Tiacci, Erik Ladewig, Gianluca Schiavoni et al. · Blood · 2018 · 234 citations · Full text

Life Sciences, Genetics, Molecular Genetics +9

Disease-associated mutation in <i>SRSF2</i> misregulates splicing by altering RNA-binding affinities

Jian Zhang, Yen K. Lieu, Abdullah Mahmood Ali et al. · Proceedings of the National Academy of Sciences · 2015 · 207 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia

Koichi Oshima, Hossein Khiabanian, Ana C. da Silva-Almeida et al. · Proceedings of the National Academy of Sciences · 2016 · 198 citations · Full text

Medicine, Genetics, Oncology +17