P. P. McCann

Polyamine Metabolism: A Potential Therapeutic Target in Trypanosomes

Carol Bacchi, Henry C. Nathan, S. H. Hutner et al. · Science · 1980 · 391 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Difluoromethylornithine irreversibly inactivates ornithine decarboxylase of <i>Pseudomonas aeruginosa</i>, but does not inhibit the enzymes of <i>Escherichia coli</i>

A. Kallio, P. P. McCann · Biochemical Journal · 1981 · 53 citations · Full text

Life Sciences, Pharmacology, Drug Metabolism +13

Catalytic irreversible inhibition of bacterial and plant arginine decarboxylase activities by novel substrate and product analogues

Alan J. Bitonti, Patrick Casara, P. P. McCann et al. · Biochemical Journal · 1987 · 47 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

Experimental Fecal Transmission of Human Cryptosporidia to Pigs, and Attempted Treatment with an Ornithine Decarboxylase Inhibitor

Harley W. Moon, Alexander Schwartz, Michael J. Welch et al. · Veterinary Pathology · 1982 · 46 citations

Life Sciences, Microbiology, Veterinary Microbiology +14

Dicyclohexylamine effects on HTC cell polyamine content and ornithine decarboxylase activity

John C. Mitchell, Donald E. Mahan, P. P. McCann et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 1985 · 43 citations

Medicine, Biochemistry, Pharmacology +8