T F Franke

AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas.

J Q Cheng, Andrew K. Godwin, Alfonso Bellacosa et al. · Proceedings of the National Academy of Sciences · 1992 · 737 citations · Full text

Entire Coding Region, Amplified Sequences, Protein-serine/threonine Kinases +15

Astrocyte elevated gene-1 activates cell survival pathways through PI3K-Akt signaling

Seok‐Geun Lee, Z-Z Su, Luni Emdad et al. · Oncogene · 2007 · 213 citations

Signal Transduction, Signaling Pathway, Glioma +7

Structure, expression and chromosomal mapping of c-akt: relationship to v-akt and its implications.

Alfonso Bellacosa, T F Franke, María Eugenia González et al. · PubMed · 1993 · 176 citations

The proteins encoded by c-akt and v-akt differ in post-translational modification, subcellular localization and oncogenic potential.

Naheed N. Ahmed, T F Franke, Alfonso Bellacosa et al. · PubMed · 1993 · 166 citations

Divergent regulation of Akt1 and Akt2 isoforms in insulin target tissues of obese Zucker rats.

Y B Kim, Odile D. Peroni, T F Franke et al. · Diabetes · 2000 · 110 citations · Full text

Insulin Signaling, Obesity, Metabolic Syndrome +22