Rational Design of Potent, Small, Synthetic Allosteric Inhibitors of Thrombin

Preetpal S. Sidhu, Aiye Liang, Akul Y. Mehta, +3

Journal of Medicinal Chemistry

Benzofuran ScaffoldSulfated Benzofuran LibraryPharmacotherapyPharmaceutical ChemistryMolecular Pharmacology +15

Interaction of Antithrombin with Sulfated, Low Molecular Weight Lignins

Brian L. Henry, Justin G. Connell, Aiye Liang, +2

Journal of Biological Chemistry

Protein AssemblyGlycobiologyMolecular BiologyPolysaccharideChemical Biology +15

First steps in the direction of synthetic, allosteric, direct inhibitors of thrombin and factor Xa

Jenson Verghese, Aiye Liang, Preet Pal Singh Sidhu, +3

Bioorganic & Medicinal Chemistry Letters

ThrombopoiesisThrombosisBiochemistryBlood PlateletMedicine +10

Designing Allosteric Regulators of Thrombin. Monosulfated Benzofuran Dimers Selectively Interact With Arg173 of Exosite 2 to Induce Inhibition

May H. Abdel Aziz, Preetpal S. Sidhu, Aiye Liang, +5

Journal of Medicinal Chemistry

Allosteric RegulatorsProteinlipid InteractionInduce InhibitionChemical BiologyThrombin Inhibition Potency +16

Visual and photometric determination of histamine using unmodified gold nanoparticles

Conghui Huang, Shuzhan Wang, Wenfeng Zhao, +4

Microchimica Acta

NanoparticlesNanomedicineEngineeringMetal NanoparticlesNanobiotechnology +10

Designing Nonsaccharide, Allosteric Activators of Antithrombin for Accelerated Inhibition of Factor Xa

Rami A. Al‐Horani, Aiye Liang, Umesh R. Desai

Journal of Medicinal Chemistry

Antithrombin InhibitionGlycobiologyChemical BiologyFocused LibraryBioanalysis +15

Sensing of hydrogen peroxide and glucose in human serum via quenching fluorescence of biomolecule-stabilized Au nanoclusters assisted by the Fenton reaction

Chenghua Zong, Min Wang, Bo Li, +5

RSC Advances

Biomolecule-stabilized Au NanoclustersSensitive DetectionAdvanced Oxidation ProcessEngineeringChemistry +16

Studying protein‐drug interaction by microfluidic chip affinity capillary electrophoresis with indirect laser‐induced fluorescence detection

Xiaojun Liu, Xin Liu, Aiye Liang, +5

Electrophoresis

On designing non-saccharide, allosteric activators of antithrombin

Arjun Raghuraman, Aiye Liang, Chandravel Krishnasamy, +3

European Journal of Medicinal Chemistry

BiochemistryNatural SciencesDrug DiscoveryBioconjugationMechanism Of Action +4

Sulfated, low molecular weight lignins inhibit a select group of heparin-binding serine proteases

Brian L. Henry, Jay N. Thakkar, Aiye Liang, +1

Biochemical and Biophysical Research Communications

Protein ChemistryProtein FunctionLow Molecular WeightBiochemistryNatural Sciences +5