Kosuke Nagai

Neutrophil Elastase Subverts the Immune Response by Cleaving Toll-Like Receptors and Cytokines in Pneumococcal Pneumonia

Hisanori Domon, Kosuke Nagai, Tomoki Maekawa et al. · Frontiers in Immunology · 2018 · 70 citations · Full text

Streptococcus pneumoniae disrupts pulmonary immune defence via elastase release following pneumolysin-dependent neutrophil lysis

Hisanori Domon, Masataka Oda, Tomoki Maekawa et al. · Scientific Reports · 2016 · 58 citations · Full text

An injectable hydrogel‐formulated inhibitor of prolyl‐4‐hydroxylase promotes T regulatory cell recruitment and enhances alveolar bone regeneration during resolution of experimental periodontitis

Kosuke Nagai, Hidetaka Ideguchi, Tetsuhiro Kajikawa et al. · The FASEB Journal · 2020 · 44 citations · Full text

Antimicrobial susceptibility of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis clinical isolates from children with acute otitis media in Japan from 2014 to 2017

Kosuke Nagai, Osamu Kimura, Hisanori Domon et al. · Journal of Infection and Chemotherapy · 2018 · 32 citations

Streptococcus Pneumoniae, Antimicrobial Susceptibility, Antibiotics +10

Pneumococcal DNA-binding proteins released through autolysis induce the production of proinflammatory cytokines via toll-like receptor 4

Kosuke Nagai, Hisanori Domon, Tomoki Maekawa et al. · Cellular Immunology · 2018 · 24 citations

Inflammation, Toll-like Receptors, Cytokine +10