M. Harsha Raj

A new pyrrole based small molecule from Tinospora cordifolia induces apoptosis in MDA-MB-231 breast cancer cells via ROS mediated mitochondrial damage and restoration of p53 activity

Kothary Rashmi, M. Harsha Raj, Manoj Paul et al. · Chemico-Biological Interactions · 2018 · 48 citations

Life Sciences, Cell Biology, Oncology +17

Combinatorial treatment with anacardic acid followed by TRAIL augments induction of apoptosis in TRAIL resistant cancer cells by the regulation of p53, MAPK and NFκβ pathways

M. Harsha Raj, B K Yashaswini, Bharathi P. Salimath · APOPTOSIS · 2016 · 27 citations

Medicine, Oncology, Pharmacology +17

Synthesis and biological evaluation of novel isoxazolines linked via piperazine to 2- benzoisothiazoles as potent apoptotic agents

Sathish Byrappa, M. Harsha Raj, Tenzin Kungyal et al. · European Journal of Medicinal Chemistry · 2016 · 20 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

A pyrrole-based natural small molecule mitigates HSP90 expression in MDA-MB-231 cells and inhibits tumor angiogenesis in mice by inactivating HSF-1

Kothary Rashmi, Hanudatta S. Atreya, M. Harsha Raj et al. · Cell Stress and Chaperones · 2017 · 15 citations · Full text

Medicine, Oncology, Pharmacology +13